Detalhe da pesquisa
1.
Insertion of a synthetic switch into insulin provides metabolite-dependent regulation of hormone-receptor activation.
Proc Natl Acad Sci U S A
; 118(30)2021 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34290145
2.
Evolution of insulin at the edge of foldability and its medical implications.
Proc Natl Acad Sci U S A
; 117(47): 29618-29628, 2020 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33154160
3.
Brain age vector: A measure of brain aging with enhanced neurodegenerative disorder specificity.
Hum Brain Mapp
; 43(16): 5017-5031, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36094058
4.
"Register-shift" insulin analogs uncover constraints of proteotoxicity in protein evolution.
J Biol Chem
; 295(10): 3080-3098, 2020 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32005662
5.
Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding.
J Biol Chem
; 293(1): 69-88, 2018 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29114034
6.
An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein.
J Biol Chem
; 293(1): 47-68, 2018 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29114035
7.
Human Sex Determination at the Edge of Ambiguity: INHERITED XY SEX REVERSAL DUE TO ENHANCED UBIQUITINATION AND PROTEASOMAL DEGRADATION OF A MASTER TRANSCRIPTION FACTOR.
J Biol Chem
; 291(42): 22173-22195, 2016 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27576690
8.
Protective hinge in insulin opens to enable its receptor engagement.
Proc Natl Acad Sci U S A
; 111(33): E3395-404, 2014 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25092300
9.
Biophysical optimization of a therapeutic protein by nonstandard mutagenesis: studies of an iodo-insulin derivative.
J Biol Chem
; 289(34): 23367-81, 2014 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24993826
10.
Mapping Multi-Modal Brain Connectome for Brain Disorder Diagnosis via Cross-Modal Mutual Learning.
IEEE Trans Med Imaging
; 43(1): 108-121, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37440391
11.
A Chebyshev Confidence Guided Source-Free Domain Adaptation Framework for Medical Image Segmentation.
IEEE J Biomed Health Inform
; PP2024 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38809721
12.
BrainMass: Advancing Brain Network Analysis for Diagnosis with Large-scale Self-Supervised Learning.
IEEE Trans Med Imaging
; PP2024 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38875087
13.
Ultra-stable insulin-glucagon fusion protein exploits an endogenous hepatic switch to mitigate hypoglycemic risk.
bioRxiv
; 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38826486
14.
A deep connectome learning network using graph convolution for connectome-disease association study.
Neural Netw
; 164: 91-104, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37148611
15.
Evaluating the resource curse hypothesis and the interplay of financial development, human development, and political stability in seven emerging economies.
Environ Sci Pollut Res Int
; 30(50): 109559-109570, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37775636
16.
The effect of externally applied traditional Chinese medicine in diabetic foot: A systematic review and meta-analysis of 34 RCTs.
Foot (Edinb)
; 56: 102045, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37499379
17.
CReg-KD: Model refinement via confidence regularized knowledge distillation for brain imaging.
Med Image Anal
; 89: 102916, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37549611
18.
Prognostic value of sarcopenia in older adults with transcatheter aortic valve implantation: A systematic review and meta-analysis.
Arch Gerontol Geriatr
; 115: 105125, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37481845
19.
Prognostic value of temporal muscle thickness, a novel radiographic marker of sarcopenia, in patients with brain tumor: A systematic review and meta-analysis.
Nutrition
; 112: 112077, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37236042
20.
MRF-Net: A multi-branch residual fusion network for fast and accurate whole-brain MRI segmentation.
Front Neurosci
; 16: 940381, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36172041