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1.
Int Urogynecol J ; 2024 Jun 20.
Artigo em Inglês | MEDLINE | ID: mdl-38900162

RESUMO

INTRODUCTION AND HYPOTHESIS: The objective was to assess intraoperative and postoperative complication rates, along with perioperative and surgical outcomes, following single-port robotics-assisted sacrocolpopexy. METHODS: This retrospective case series included 200 patients who underwent single-port robotics-assisted sacrocolpopexy to treat Pelvic Organ Prolapse Quantification (POPQ) stage 2-4 symptomatic prolapse between April 2020 and August 2023 by a single surgeon. Intraoperative and postoperative complications and perioperative outcomes were evaluated for all the patients, whereas surgical outcomes for 74 patients were assessed at 1-year follow-up. Surgical failure was defined as the presence of any of the following: the presence of vaginal bulging symptoms, any prolapse beyond the hymen, or retreatment for prolapse. RESULTS: During the study period, 200 single-port robotics-assisted sacrocolpopexies were performed. The median age and body mass index were 65.0 years and 24.6 kg/m2 respectively. Most patients had POPQ stage 3 or 4 prolapse and underwent concomitant total hysterectomy. The median total operation time was 212.0 min, and none of the patients required conversion to laparoscopy or laparotomy. The intraoperative cystotomy rate was 2.5%, and one patient had a blood transfusion owing to presacral vessel injury. Postoperative complications of mesh exposure and wound hernia were 0.5% and 2.0% respectively. At 1 year postoperatively, the rate of composite surgical failure was 9.5%, with a 5.4% anatomical recurrence rate. None of the patients experienced apical prolapse recurrence, and one received anterior colporrhaphy for anterior compartment prolapse recurrence. CONCLUSIONS: Single-port robotics-assisted sacrocolpopexy is safe and effective, with low complication rates and favorable perioperative and surgical outcomes.

2.
J Minim Invasive Gynecol ; 30(4): 277-283, 2023 04.
Artigo em Inglês | MEDLINE | ID: mdl-36528258

RESUMO

STUDY OBJECTIVE: To investigate the feasibility and predictive factors for same-day discharge (SDD) after robotic hysterectomy (RH) for benign indications to optimize patient selection by incorporating preoperative, intraoperative, and postoperative variables. DESIGN: A single-center retrospective cohort study. SETTING: Tertiary academic hospital. PATIENTS: Patients undergoing RH for benign indications. INTERVENTIONS: Patients were designated for SDD by implementing enhanced recovery after surgery protocol. MEASUREMENTS AND MAIN RESULTS: The study included 890 patients who underwent RH for benign indications between the years 2016 and 2021. Of these, 618 (69.4%) were discharged the same day and 272 (30.5%) were admitted for overnight stay. Both groups had similar age (46.4 vs 46.2 years), body mass index (28.3 vs 28.9), and indications for surgery. In multivariable logistic regression, factors that were significant for overnight stay were American Society of Anesthesiologists score 3, Charlson comorbidity index, previous laparotomy, and operative time. Other factors such as surgery start time and preoperative hemoglobin levels were not statistically significant. Postoperative outcomes were comparable for both groups with similar readmission and reoperation rates. CONCLUSION: The likelihood of SDD after RH in this cohort after implementing enhanced recovery after surgery protocol was almost 70%, and most of the predictive factors for overnight stay were nonmodifiable. Importantly, both groups had similar outcomes after surgery.


Assuntos
Procedimentos Cirúrgicos Robóticos , Feminino , Humanos , Pessoa de Meia-Idade , Estudos Retrospectivos , Procedimentos Cirúrgicos Robóticos/efeitos adversos , Procedimentos Cirúrgicos Robóticos/métodos , Alta do Paciente , Estudos de Viabilidade , Histerectomia/efeitos adversos , Histerectomia/métodos , Complicações Pós-Operatórias/etiologia , Tempo de Internação , Readmissão do Paciente
3.
Medicina (Kaunas) ; 59(10)2023 Oct 12.
Artigo em Inglês | MEDLINE | ID: mdl-37893536

RESUMO

Introduction: Concomitant nerve injuries with musculoskeletal injuries present a challenging problem. The goals of nerve reconstruction for the shoulder include shoulder abduction and external rotation. When patients fail to achieve acceptable shoulder external rotation and shoulder abduction, tendon transfers such as trapezius transfer offer a reliable option in the subsequent stage. Case Presentation: A 32-year-old male presented with weak external rotation in his left shoulder, after previous axillary nerve reconstruction. He received the ipsilateral lower trapezius transfer with the aim of improving the external rotation. Discussion: The lower trapezius restores a better joint reaction force in both the compressive-distractive and anterior-posterior balancing and provides a centering force through the restoration of the anterior-posterior force couple. Conclusion: We believe that the ipsilateral lower trapezius transfer to the infraspinatus is a good outcome and is effective in improving overall shoulder stability and the shoulder external rotation moment arm or at least maintaining in neutral position with the arm fully adducted in patients with post axillary nerve injuries post unsatisfactory nerve reconstruction to increase the quality of life and activities of daily living.


Assuntos
Lesões do Manguito Rotador , Músculos Superficiais do Dorso , Masculino , Humanos , Adulto , Lesões do Manguito Rotador/complicações , Lesões do Manguito Rotador/cirurgia , Músculos Superficiais do Dorso/cirurgia , Transferência Tendinosa , Atividades Cotidianas , Qualidade de Vida , Amplitude de Movimento Articular/fisiologia , Resultado do Tratamento
4.
J Minim Invasive Gynecol ; 29(7): 879-883, 2022 07.
Artigo em Inglês | MEDLINE | ID: mdl-35460879

RESUMO

STUDY OBJECTIVE: To determine whether advancing a manipulator increased the distance of the ureter to the cervix and/or vagina. DESIGN: Prospective. SETTING: Academic institution. PATIENTS: A total of 22 intact fresh-frozen female pelvises. INTERVENTIONS: A total of 6 ureteral distances were measured per pelvis. Included were the following measurements on each side: (1) from the lateral cervical wall to the ureter at the intersection with the uterine artery; (2) from the lateral cervical wall to the parametrial ureter; and (3) from the vagina to the ureter at the intersection with the uterine artery. All measurements were obtained with and without advancement of a uterine manipulator. MEASUREMENTS AND MAIN RESULTS: The average distance from the ureter to the cervix and vagina without advancing the manipulator was 2.8 and 3.1 cm, respectively, and the distance from the parametrial ureter to the cervix was 3.3 cm. When the manipulator was advanced, all ureteral distances increased by 0.8, 0.6, and 0.6 cm, respectively, in 12 of the 22 pelvises (55%). Advancing the manipulator did not increase at least 1 of the distances in 10 of the 22 pelvises (45%). The advancement of the manipulator lengthened the 2 shortest ureteral distances of 1 cm noted in 1 pelvis (4.5%) by 0.9 and 0.4 cm. CONCLUSION: The uterine manipulator increased the distance of the ureter to the cervix and vagina for all measurements in 55.5% of the pelvises. The greatest increase was 0.9 cm. The manipulator did not increase at least 1 of the distances in 10 of the 22 pelvises (45.4%).


Assuntos
Ureter , Cadáver , Colo do Útero , Feminino , Humanos , Pelve , Estudos Prospectivos , Vagina
5.
Clin Immunol ; 232: 108874, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-34740841

RESUMO

Female sex hormones affect the immune response in the lower female genital tract. To understand their mechanisms of action, it is essential to define cell types expressing estrogen receptor (ER) and/or progesterone receptor (PR) in the human vaginal mucosa (VM). Here, we report that none of the dendritic cell (DC) subsets in the human VM expressed ERα or PR in situ. However, they were capable of expressing ERα, but not PR, after in vitro culture of the whole VM tissues. Similarly, ERα and/or PR expression by T cells in the VM tissues was also inducible rather than constitutive. In contrast, ERα and/or PR were constitutively expressed in HLA-DR- non-immune cell types (vimentin+, desmin+, or CD10+). These new findings will help us understand the mechanisms of action of female sex hormones in the modulation of immune response in the human VM and lower female genital tract.


Assuntos
Mucosa/metabolismo , Receptores de Estrogênio/biossíntese , Receptores de Progesterona/biossíntese , Vagina/metabolismo , Adulto , Idoso , Idoso de 80 Anos ou mais , Células Dendríticas/metabolismo , Feminino , Humanos , Pessoa de Meia-Idade , Linfócitos T/metabolismo
6.
J Minim Invasive Gynecol ; 28(5): 1095-1100, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-32827720

RESUMO

STUDY OBJECTIVE: To present a series of robotic laparoendoscopic single-site surgery (LESS) and reduced-port hysterectomy cases and discuss the surgical technique required for successful use on this new platform. DESIGN: Retrospective case series. SETTING: Academic medical center. PATIENTS: All patients undergoing robotic LESS or reduced-port hysterectomy with the SP1098 da Vinci SP Surgical System (Intuitive Surgical, Sunnyvale, CA) from December 2019 to March 2020. INTERVENTIONS: Robotic LESS or reduced-port hysterectomy. MEASUREMENTS AND MAIN RESULTS: A total of 8 cases of hysterectomy were performed successfully. Four cases included concomitant resection of endometriosis. Five cases required placement of an additional port. The average uterine weight was 136.1 g ± 61.5 g (range 87-246). The average estimated blood loss was 37.5 mL ± 27 mL (range 20-100). The average operative time was 86.5 minutes ± 27.1 minutes (range 60-132). The time required for vaginal cuff closure was available for patients 5 to 8, and ranged from 10 minutes to 13 minutes. All patients had same-day discharge. There were no conversions to alternative surgical modality, complications, or readmissions. CONCLUSION: Our preliminary experience with the SP1098 da Vinci SP Surgical System demonstrated the technical feasibility and safety of this surgical modality for gynecologic surgery. Additional studies examining postoperative outcomes and prospective studies comparing this modality with traditional robotic surgery are indicated.


Assuntos
Laparoscopia , Procedimentos Cirúrgicos Robóticos , Feminino , Humanos , Histerectomia , Duração da Cirurgia , Estudos Prospectivos , Estudos Retrospectivos
7.
J Minim Invasive Gynecol ; 28(3): 387, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-32673647

RESUMO

OBJECTIVE: To demonstrate identification and dissection of the pelvic autonomic nerves in gynecologic surgery. DESIGN: Identification on the right and left pelvic pelvises, dissection and preservation of the inferior hypogastric plexus in deep endometriosis, and dissection and preservation of the pelvic autonomic nerves in radical hysterectomy. SETTING: Academic center. INTERVENTIONS: Robotic excision of the pelvic peritoneum, excision of deep endometriosis in the uterosacral ligaments, and radical hysterectomy. CONCLUSION: Pelvic autonomic nerves are easy to identify with the magnification provided with an endoscopic camera. They should be dissected and preserved whenever possible because of their important function.


Assuntos
Procedimentos Cirúrgicos em Ginecologia/métodos , Tratamentos com Preservação do Órgão/métodos , Pelve/inervação , Traumatismos dos Nervos Periféricos/prevenção & controle , Dissecação , Endometriose/patologia , Endometriose/cirurgia , Feminino , Humanos , Plexo Hipogástrico/lesões , Plexo Hipogástrico/cirurgia , Histerectomia/métodos , Ligamentos/lesões , Ligamentos/inervação , Ligamentos/cirurgia , Pelve/cirurgia , Doenças Peritoneais/patologia , Doenças Peritoneais/cirurgia , Peritônio/inervação , Peritônio/cirurgia , Útero/inervação , Útero/cirurgia
8.
J Minim Invasive Gynecol ; 28(3): 475-480, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-32702513

RESUMO

OBJECTIVE: To provide a perspective on nerve-sparing (NS) surgery in gynecology. DATA SOURCES: Literature review, English language. METHODS OF STUDY SELECTION: Systematic reviews and meta-analyses studies were selected for review for oncology; comparative studies were selected for endometriosis, and 1 comparative and 1 prospective study were chosen for sacrocolpopexy. TABULATION, INTEGRATION, AND RESULTS: Two tables summarize the results of systematic reviews and meta-analyses in oncology. Oncology, endometriosis, and urogynecology sections. Primary benefit of NS technique is decreased bladder dysfunction, and, to a lesser degree, vaginal and rectal dysfunc. CONCLUSION: NS is preferable to conventional surgery for benign and malignant conditions to reduce postoperative bladder, rectal, and vaginal dysfunction.


Assuntos
Procedimentos Cirúrgicos em Ginecologia/métodos , Tecido Nervoso/cirurgia , Tratamentos com Preservação do Órgão/métodos , Endometriose/epidemiologia , Endometriose/patologia , Endometriose/cirurgia , Feminino , Doenças Urogenitais Femininas/epidemiologia , Doenças Urogenitais Femininas/patologia , Doenças Urogenitais Femininas/cirurgia , Neoplasias dos Genitais Femininos/epidemiologia , Neoplasias dos Genitais Femininos/patologia , Neoplasias dos Genitais Femininos/cirurgia , Procedimentos Cirúrgicos em Ginecologia/efeitos adversos , Procedimentos Cirúrgicos em Ginecologia/estatística & dados numéricos , Humanos , Histerectomia/métodos , Metanálise como Assunto , Tecido Nervoso/patologia , Tratamentos com Preservação do Órgão/efeitos adversos , Tratamentos com Preservação do Órgão/estatística & dados numéricos , Período Pós-Operatório , Estudos Prospectivos , Revisões Sistemáticas como Assunto
9.
J Minim Invasive Gynecol ; 28(2): 245-248, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-32389736

RESUMO

STUDY OBJECTIVE: To analyze outcomes and postoperative complications in patients undergoing robot-assisted rectus abdominis flap harvest for pelvic floor reconstruction. DESIGN: Case series. SETTING: Academic setting. PATIENTS: Pelvic reconstruction surgery patients. INTERVENTIONS: The rectus abdominis muscle flap can be used as a flap for pelvic reconstruction, providing a large volume of soft tissue that can be used in the treatment of many comorbid conditions, including genital fistulas, postradiation pelvic exenteration, and abdominoperineal resection defects. Intraperitoneal harvest of the rectus muscle using a robotic approach allows avoidance of laparotomy and subsequent disruption of the anterior rectus sheath, thus preserving the integrity of the abdominal wall. MEASUREMENTS AND MAIN RESULTS: A retrospective analysis of patient demographic and clinical characteristics was performed for all patients who underwent robot-assisted rectus abdominis flap harvest for pelvic floor reconstruction at our institution from October 1, 2016, to October 31, 2018. The postoperative complications analyzed included bowel obstructions, surgical site infections, emergency room visits, and need for readmission. Six patients (4 women and 2 men), with a mean age of 69.2 years (range = 57-79 years) and median follow-up time of 9.2 months (range = 5-12 months), were included. Muscle flap harvest was performed on the right side in 4 patients and on the left in 2 patients. The indications for reconstructive surgery included vesicovaginal fistula, complex pelvic organ prolapse, anterior and posterior exenteration, partial and total vaginectomy, partial vulvectomy, and abdominoperineal resection. Two patients received neoadjuvant chemoradiation. One of the 6 cases was converted to laparotomy; however, this was not owing to the rectus harvest. Three patients experienced no complications after reconstruction; 1 patient reported occasional abdominal pain; 1 patient had intermittent bowel obstruction; and 1 patient developed a pelvic abscess, requiring readmission. All 6 patients achieved satisfactory healing of the pelvic wound after robot-assisted rectus abdominis flap inset. CONCLUSION: Robot-assisted rectus abdominis flap harvest for pelvic floor reconstruction is a reliable means of defect closure, despite the presence of substantial comorbidities and risk factors in this patient cohort. Patient selection and counseling are crucial to optimize surgical outcomes in this complex population.


Assuntos
Pelve/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Reto do Abdome/transplante , Procedimentos Cirúrgicos Robóticos/métodos , Retalhos Cirúrgicos , Parede Abdominal/cirurgia , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/etiologia , Procedimentos de Cirurgia Plástica/instrumentação , Reto do Abdome/patologia , Reto do Abdome/cirurgia , Estudos Retrospectivos , Retalhos Cirúrgicos/cirurgia , Retalhos Cirúrgicos/transplante , Coleta de Tecidos e Órgãos/instrumentação , Coleta de Tecidos e Órgãos/métodos
10.
J Minim Invasive Gynecol ; 28(4): 872-880, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-32805461

RESUMO

STUDY OBJECTIVE: To determine patterns and barriers for referral to fellowship-trained minimally invasive gynecologic surgeons. DESIGN: Questionnaire. SETTING: United States and its territories and Canada. PARTICIPANTS: Actively practicing general obstetrician/gynecologists (OB/GYNs). INTERVENTIONS: Internet-based survey. MEASUREMENTS AND MAIN RESULTS: Of 157 respondents, 144 (91.7%) general OB/GYNs were included. Subspecialty fellowship training resulted in the exclusion of 13 (8.3%) respondents. A total of 86 respondents (59.7%) considered referral to fellowship-trained minimally invasive gynecologic surgery (MIGS) subspecialists. The top 3 cited reasons for nonreferral were adequate residency training (n = 84, 58.3%), preference for continuity of care (n = 48, 33.3%), and preference for referral to other subspecialists (n = 46, 31.9%). The top 3 cited reasons for referral to MIGS subspecialists were complex pathology (n = 92, 63.9%), complex medical and/or surgical history (n = 76, 52.8%), and out of scope of practice (n = 53, 36.8%). If providers required intraoperative assistance, respondents consulted an OB/GYN colleague with comparable training (n = 50, 34.7%), gynecologic oncologist (n = 48, 33.3%), or non-OB/GYN surgical subspecialist (n = 33, 22.9%). Factors that were not associated with the decision to refer to MIGS subspecialists included years in practice (p = .13), additional training experiences beyond residency (p = .45), and number of hysterectomies performed by laparotomy (p = .69). Self-reported high-volume surgeons (p <.01) were less likely to refer. In contrast, providers who self-reported as low-volume surgeons (p = .02) and were aware of MIGS subspecialists in the community (p <.01) were more likely to consider referral. Respondents reported using a laparoscopic approach to hysterectomy most frequently (n = 79, 54.9%). In contrast, 36.8% preferred the laparoscopic route for themselves or their partner, whereas 48.6% preferred the vaginal approach. CONCLUSION: Most of the general OB/GYNs would consider referral to fellowship-trained MIGS subspecialists. Providers who reported adequate residency training and those who preferred continuity of care or referral to other surgical subspecialists were less likely to refer to MIGS subspecialists.


Assuntos
Ginecologia , Internato e Residência , Bolsas de Estudo , Feminino , Ginecologia/educação , Humanos , Histerectomia , Procedimentos Cirúrgicos Minimamente Invasivos , Encaminhamento e Consulta , Estados Unidos
11.
J Ultrasound Med ; 40(4): 839-843, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32870519

RESUMO

The diagnosis of ovarian torsion is challenging and relies mostly on morphologic findings. Occasionally, women or children with acute pelvic pain who have undergone an initial ultrasound (US) evaluation with results interpreted as negative for ovarian torsion will return with recurrent or increasing pain, prompting an US reevaluation. The flipped ovary sign refers to a demonstrable change in the orientation of the ovary on follow-up US examinations, recognized by changing positions of ovarian landmarks established by follicles, cysts, or masses. This sign is valuable for identifying ovarian torsion in these patients, even in the absence of classic morphologic or Doppler features of ovarian torsion.


Assuntos
Doenças Ovarianas , Torção Ovariana , Criança , Feminino , Humanos , Doenças Ovarianas/diagnóstico por imagem , Anormalidade Torcional/diagnóstico por imagem , Ultrassonografia
12.
J Ultrasound Med ; 40(6): 1091-1096, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32894615

RESUMO

OBJECTIVES: The study aim was to evaluate the diagnostic performance of the uterine sliding sign in predicting deeply infiltrating endometriosis in the setting of non-physician sonographers performing but not interpreting the maneuver. The impact of uterine sliding sign has not been previously demonstrated in this practice setting. METHODS: Physicians' remote interpretations of transvaginal ultrasound examinations in 2016, before uterine sliding sign, were compared to examinations in 2019 after addition of uterine sliding sign to determine the diagnostic rates. Surgical and histopathological results were reviewed to determine sensitivity and specificity of the respective exam techniques. RESULTS: Two hundred eighty-five transvaginal ultrasounds were performed in 2016 and 390 sliding sign ultrasounds in 2019. The number of deeply infiltrating endometriosis cases identified increased significantly from 2% to 6% during the study period (chi-square, Fisher's exact test p = .012). The sensitivity and specificity of routine pelvic sonography for detecting deeply infiltrating endometriosis improved from 36%/94% to 68%/98%. CONCLUSIONS: Uterine sliding sign videos should be included in the standard sonographic protocol for patients presenting with chronic pelvic pain, endometriosis history, or sonographic evidence of endometriosis in the setting of physicians interpreting sonographic images obtained by non-physicians.


Assuntos
Endometriose , Endometriose/diagnóstico por imagem , Feminino , Humanos , Dor Pélvica , Sensibilidade e Especificidade , Ultrassonografia
13.
Gynecol Oncol ; 157(2): 476-481, 2020 05.
Artigo em Inglês | MEDLINE | ID: mdl-32107048

RESUMO

OBJECTIVES: To report the impact of implementing standardized guidelines for opioid prescriptions after gynecologic surgery and describe patient perspectives before and after implementation for those undergoing laparotomy for ovarian cancer. METHODS: Patients undergoing gynecologic surgery between October 2017 and May 2018 were prescribed opioids at discharge using tiered guidelines; prescriptions were compared to consecutive historical controls (March 2017-October 2017). A subset of ovarian cancer laparotomy patients were surveyed regarding postoperative opioid consumption and patient experience. RESULTS: A total of 620 women in the tiered guideline cohort were compared with 599 historical controls. Following implementation, 95.8% of prescriptions met guidelines. Median milligram morphine equivalents (MME) prescribed decreased from 150 to 75 (p ≤ 0.001) with no change in opioid refills (7.7 vs 6.9%, p = 0.62). In surveyed ovarian cancer patients, 100% of tiered guideline patients and 92% of historical controls felt satisfied with pain control (p = 0.24), despite a 50% reduction in prescribed MME and 14.6% receiving no opioids at discharge (p = 0.002). The median (IQR) MME consumed after discharge was 15 (0, 75) in tiered guideline patients vs. 24 (0, 135) in historical controls, and 38.2% and 42.4% consumed no opioids, respectively. Mean time between surgery and opioid use cessation was <1 week in both groups; patients' perceptions of opioid prescription appropriateness did not change (p = 0.49). More than 75% of patients kept their remaining opioids rather than dispose of them. CONCLUSIONS: Reducing prescribed opioids after gynecologic surgery using tiered guidelines did not increase opioid refills or worsen patients' perceptions of postoperative pain. Even after laparotomy, very little opioids were required over a short duration after dismissal. Infrequent disposal of leftover opioids highlights the need to avoid over-prescribing.


Assuntos
Analgésicos Opioides/administração & dosagem , Neoplasias Ovarianas/cirurgia , Manejo da Dor/normas , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/prevenção & controle , Satisfação do Paciente , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos de Casos e Controles , Estudos de Coortes , Feminino , Procedimentos Cirúrgicos em Ginecologia/efeitos adversos , Procedimentos Cirúrgicos em Ginecologia/métodos , Humanos , Pessoa de Meia-Idade , Manejo da Dor/métodos , Guias de Prática Clínica como Assunto , Prescrições/normas , Estudos Retrospectivos , Adulto Jovem
14.
Gynecol Oncol ; 156(2): 320-327, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31843274

RESUMO

OBJECTIVE: To investigate progression-free survival (PFS) and overall survival (OS) between women who underwent surgical versus radiographic assessment of pelvic lymph nodes (PLN) and para-aortic lymph nodes (PALN) prior to chemoradiation therapy for cervical cancer. METHODS: In this retrospective cohort analysis, patients with stage IB2 - IIIB squamous cell, adenocarcinoma and adenosquamous carcinoma of the cervix who completed concurrent chemoradiation therapy (CCRT) between 2000 and 2017 from the Mayo Clinic Cancer Registry were identified. A 1:2 propensity score matching between surgical and imaging groups was performed and PFS and OS were compared between groups. RESULTS: 148 patients were identified and after propensity score matching, 35 from the surgical group and 70 from the imaging group were included in the analysis. There were no statistical differences in baseline characteristics between the 2 groups. The median follow-up time was 41 months (range 7-218) for the surgical group and 51.5 months (range 7-198) for the imaging group. Five-year PFS was 62.6% for the surgical group and 72.4% in imaging group (HR 1.11, 95% CI 0.54-2.30, p = 0.77). Five-year OS was 70.2% for the surgical group and 70.5% for the imaging group (HR 1.02, 95% CI 0.46-2.29, p = 0.96). FIGO stage, PALN metastasis, and parametrial involvement were found to be poor prognosticators for PFS and OS in univariate analysis. Only PALN metastasis significantly predicted unfavorable PFS (HR 2.76, 95% CI 1.23-6.18, p = 0.01) and OS (HR 3.46, 95% CI 1.40-8.55, p = 0.01) in multivariate analysis. There were no differences in locoregional recurrence and distant metastasis between the two groups (p = 0.33 and 0.59 respectively). CONCLUSION: Patients with cervical cancer who underwent radiographic assessment of PLN and PALN had comparable survival outcomes to surgical assessment.


Assuntos
Linfonodos/diagnóstico por imagem , Linfonodos/cirurgia , Neoplasias do Colo do Útero/diagnóstico por imagem , Neoplasias do Colo do Útero/cirurgia , Quimiorradioterapia , Feminino , Humanos , Linfonodos/patologia , Metástase Linfática , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Intervalo Livre de Progressão , Pontuação de Propensão , Estudos Retrospectivos , Neoplasias do Colo do Útero/patologia , Neoplasias do Colo do Útero/terapia
15.
Dis Colon Rectum ; 63(9): 1334-1337, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-33216503

RESUMO

INTRODUCTION: As multidisciplinary treatment modalities for rectal cancer continue to evolve, neoadjuvant chemoradiation then surgical resection is a common approach. Robotic-assisted abdominoperineal resection is becoming more prevalent in part because of better visualization and instrument mobility within the pelvis. After abdominoperineal resection, postoperative perineal wound complications remain a significant risk. Pelvic reconstruction lowers this risk, and a pedicled rectus abdominis muscle flap is frequently used to achieve this. Traditional flap harvest requires laparotomy, resulting in violation of both rectus sheaths and a large midline scar. Robotic harvest of the rectus abdominis muscle for pelvic reconstruction after abdominoperineal resection is a novel approach with foreseeable benefits. TECHNIQUE: After completion of abdominoperineal resection, 2 additional trocars are inserted in the lateral abdomen, and the robot is reoriented toward the posterior abdominal wall. The peritoneum and posterior rectus sheath are incised, and dissection is carried superiorly and inferiorly in a sagittal plane to reveal the rectus abdominis muscle. The muscle body is separated from the anterior rectus sheath. Once the inferior epigastric artery is identified, the superior pole of the muscle is transected. Continued lateral dissection ensures flap mobility for placement within the pelvis. After obtaining proper reach, the robot is undocked, and the flap is sutured in place through the perineal defect. RESULTS: After trocar placement and robot repositioning, both the colorectal and plastic surgeons trade places at the console. Robotic flap harvest precludes the need for laparotomy. The anterior rectus sheath remains unviolated and the patient avoids an additional midline scar. The aforementioned benefits of robot-assisted abdominoperineal resection, namely increased visualization and maneuverability, were also found applicable when robotically harvesting this flap. CONCLUSIONS: This technique exemplifies an additional minimally invasive technique for patients pursuing abdominoperineal resection. With knowledge of this novel approach, surgeons can better tailor their operations to benefit the patient.


Assuntos
Períneo/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Protectomia/métodos , Reto do Abdome/transplante , Procedimentos Cirúrgicos Robóticos/métodos , Retalhos Cirúrgicos/transplante , Cirurgia Colorretal , Humanos , Procedimentos Cirúrgicos Minimamente Invasivos , Terapia Neoadjuvante , Cirurgia Plástica
16.
J Minim Invasive Gynecol ; 27(7): 1603-1609, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32156584

RESUMO

STUDY OBJECTIVE: To compare the incidence of perioperative complications of total vaginal hysterectomy (TVH) in women with and without a prior cesarean section (CS). DESIGN: Retrospective cohort. SETTING: Tertiary care academic institution. PATIENTS: A total of 742 women who underwent TVH over a 5-year period. INTERVENTIONS: TVH. MEASUREMENTS AND MAIN RESULTS: Prior CS did not increase the overall rate of Clavien-Dindo grades 2 to 3 complications (p =.20). The incidence of cystotomy (2.2% CS vs 1.1% no CS, p =.29), ureteral injury (1.1% vs 0.2%, p =.23), proctotomy (1.1% vs 0.2%, p =.23), postoperative bleeding (1.1% vs 0.6%, p =.47), or reoperation (0.0% vs 0.3%, p = 1.00) was not increased from having a prior CS. Prior CS increased blood transfusion (5.6% vs 0.6%, p <.05) but did not increase conversion to laparotomy (2.2% vs 0.6%, p =.15), length of hospitalization (11.2% vs 14.1% discharge on the same day, 66.3% vs 63.6% discharge on postoperative day 1, and 22.5% vs 22.4% discharge on or after postoperative day 2, p =.76), or 30-day readmission rates (1.1% vs 3.5%, p =.34). CONCLUSION: In patients who underwent TVH, a prior CS increased postoperative blood transfusion but did not increase the risk for overall perioperative complications.


Assuntos
Cesárea , Histerectomia Vaginal , Adulto , Idoso , Cesárea/efeitos adversos , Cesárea/estatística & dados numéricos , Estudos de Coortes , Feminino , Humanos , Histerectomia Vaginal/efeitos adversos , Histerectomia Vaginal/métodos , Histerectomia Vaginal/estatística & dados numéricos , Incidência , Laparotomia/estatística & dados numéricos , Pessoa de Meia-Idade , Alta do Paciente , Readmissão do Paciente/estatística & dados numéricos , Período Perioperatório , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Gravidez , Reoperação/estatística & dados numéricos , Estudos Retrospectivos , Resultado do Tratamento
17.
J Minim Invasive Gynecol ; 27(2): 498-503.e1, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-30980994

RESUMO

STUDY OBJECTIVE: To determine the safety and feasibility of same-day discharge (SDD) in patients undergoing vaginal hysterectomy with pelvic floor reconstruction. DESIGN: Prospective cohort pilot study. SETTING: Single academic medical center. PATIENTS: Women undergoing vaginal hysterectomy with pelvic floor reconstruction were considered for inclusion in the study. INTERVENTIONS: SDD or overnight hospitalization after surgery. MEASUREMENTS AND MAIN RESULTS: A total cohort of 55 women undergoing vaginal hysterectomy and pelvic floor reconstruction for pelvic organ prolapse and/or urinary incontinence was identified. The control group consisted of 19 women who were planned for overnight hospitalization. The intervention group had 36 women who were planned for SDD. In the intervention group 63.9% of patients (n = 23) were successfully discharged home and 36.1% (n = 13) required an unplanned overnight admission. Reasons for unplanned admission included persistent anesthetic effects (dizziness/nausea/drowsiness, n = 9, 69%), uncontrolled pain (n = 1, 7.7%), fever (n = 1, 7.7%), anemia (n = 2, 15.4%), with return to operating room for hematoma evacuation (n = 1, 7.7%). A voiding trial was passed on the first attempt in 30 patients (54.5%). The percentage of successful voiding trials on the first attempt was 30.8% for patients requiring unplanned admission and 78.9% for patients with planned overnight hospitalization (p = .011). There were no significant differences in the number of emergency department visits (p = .677) or unplanned office visits (p = .193) between the control and intervention groups. CONCLUSION: SDD after vaginal hysterectomy with pelvic floor reconstruction appears to be safe and feasible. Patients who were discharged the same day did not require a higher volume of emergency department or office evaluations.


Assuntos
Procedimentos Cirúrgicos Ambulatórios , Recuperação Pós-Cirúrgica Melhorada , Histerectomia Vaginal , Diafragma da Pelve/cirurgia , Prolapso de Órgão Pélvico/cirurgia , Procedimentos de Cirurgia Plástica , Incontinência Urinária/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Procedimentos Cirúrgicos Ambulatórios/efeitos adversos , Procedimentos Cirúrgicos Ambulatórios/métodos , Procedimentos Cirúrgicos Ambulatórios/estatística & dados numéricos , Estudos de Coortes , Feminino , Procedimentos Cirúrgicos em Ginecologia/efeitos adversos , Procedimentos Cirúrgicos em Ginecologia/métodos , Procedimentos Cirúrgicos em Ginecologia/estatística & dados numéricos , Hospitalização/estatística & dados numéricos , Humanos , Histerectomia Vaginal/efeitos adversos , Histerectomia Vaginal/métodos , Histerectomia Vaginal/estatística & dados numéricos , Pessoa de Meia-Idade , Alta do Paciente/estatística & dados numéricos , Prolapso de Órgão Pélvico/epidemiologia , Projetos Piloto , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/terapia , Procedimentos de Cirurgia Plástica/efeitos adversos , Procedimentos de Cirurgia Plástica/métodos , Procedimentos de Cirurgia Plástica/estatística & dados numéricos , Incontinência Urinária/epidemiologia
18.
J Minim Invasive Gynecol ; 27(3): 681-686, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31201940

RESUMO

STUDY OBJECTIVE: To identify risk factors associated with postoperative urinary retention in patients undergoing outpatient minimally invasive hysterectomy. DESIGN: A retrospective cohort study. SETTING: An academic medical center. PATIENTS: All patients undergoing outpatient minimally invasive hysterectomy between January 2013 and July 2018 were considered for inclusion in the study. INTERVENTIONS: Outpatient laparoscopic, vaginal, or robotically assisted laparoscopic hysterectomy. MEASUREMENTS AND MAIN RESULTS: Four hundred forty-four patients met the inclusion criteria. Postoperative urinary retention occurred in 94 patients, and 347 patients successfully passed their voiding trial in the postanesthesia care unit for a pass rate of 79%. Demographic characteristics were similar, except patients who experienced postoperative urinary retention were less likely to be menopausal (23.4% vs 34.7%, p = .038). Those with urinary retention received more perioperative opioids (morphine milligram equivalent of 14.4 mg vs11.2 mg, p = .012), had longer operative times (122.9 ± 55.6 vs 95.7 ± 42.3 minutes, p < .01), and experienced more blood loss (105.3 ± 134.4 vs 78.5 ± 86.8 mL, p = .025). The rate of urinary tract infections was similar. Logistic regression analysis showed that the route of hysterectomy and age were not associated with an increased risk for urinary retention, whereas a longer operative time and higher doses of perioperative opioid use were. CONCLUSION: In patients undergoing minimally invasive outpatient hysterectomy, a longer operative time and increased perioperative narcotic use increases the risk of postoperative urinary retention.


Assuntos
Assistência Ambulatorial , Histerectomia/efeitos adversos , Complicações Pós-Operatórias/diagnóstico , Retenção Urinária/diagnóstico , Retenção Urinária/etiologia , Adulto , Assistência Ambulatorial/métodos , Assistência Ambulatorial/estatística & dados numéricos , Estudos de Coortes , Feminino , Humanos , Histerectomia/métodos , Histerectomia/estatística & dados numéricos , Laparoscopia/efeitos adversos , Laparoscopia/métodos , Laparoscopia/estatística & dados numéricos , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos/efeitos adversos , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Procedimentos Cirúrgicos Minimamente Invasivos/estatística & dados numéricos , Duração da Cirurgia , Pacientes Ambulatoriais , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Prognóstico , Estudos Retrospectivos , Fatores de Risco , Procedimentos Cirúrgicos Robóticos/efeitos adversos , Procedimentos Cirúrgicos Robóticos/métodos , Procedimentos Cirúrgicos Robóticos/estatística & dados numéricos , Retenção Urinária/epidemiologia
19.
J Minim Invasive Gynecol ; 26(7): 1226, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31005582

RESUMO

STUDY OBJECTIVE: To describe a standardized technique for robotic complete excision of sacrocolpopexy mesh. DESIGN: A step by step video demonstration of the technique. SETTING: A tertiary care academic hospital. PATIENTS: Three patients with persistent pain after sacrocolpopexy mesh insertion. Although exposure can usually be controlled with partial mesh removal, complete excision may be required for patients with persistent pain, exposure, or severe infection. Because of the inherent inflammation, fibrosis, and distortion of tissue planes with mesh augmentation, removal should be performed in a methodical fashion, preparing for possible visceral injury. INTERVENTION: Robotic-assisted sacrocolpopexy mesh removal. MEASUREMENTS AND MAIN RESULTS: This video (Video 1) presents a systematic, minimally invasive approach to sacrocolpopexy mesh removal, highlighting the technical and anatomic aspects that can facilitate the procedure. Retroperitoneal dissection along with identification of the anatomic landmarks, such as the sacral promontory, iliac vessels, right ureter, bladder, and rectum, are critical. Backfilling the bladder and the use of vaginal and rectal probes can also optimize difficult tissue planes. In each compartment, identifying the whole mesh before starting its removal may prevent leaving mesh fragments. The caudal to cranial and lateral to medial approach facilitates the extraction of the synthetic tissue. Removing the sacral mesh last allows the attachment to be used as a point of traction. Superior dissection of the mesh requires careful dissection and recognition of great vessels along with autonomic nervous structures such as the superior hypogastric plexus. CONCLUSION: Minimally invasive removal of sacrocolpopexy mesh can be standardized using this step by step approach.


Assuntos
Remoção de Dispositivo/métodos , Procedimentos Cirúrgicos em Ginecologia/métodos , Procedimentos Cirúrgicos Robóticos/métodos , Telas Cirúrgicas , Feminino , Humanos , Plexo Hipogástrico , Pessoa de Meia-Idade , Prolapso de Órgão Pélvico/cirurgia , Robótica , Sacro , Ureter , Bexiga Urinária , Vagina/cirurgia
20.
J Minim Invasive Gynecol ; 26(2): 197, 2019 02.
Artigo em Inglês | MEDLINE | ID: mdl-30240900

RESUMO

STUDY OBJECTIVE: To provide surgeons with techniques for preemptive analgesia during minimally invasive gynecologic surgery. Postoperative pain management is an important component of patient care after gynecologic surgery. There have been numerous advances in pain management, including studies that show that preoperative administration of analgesics decreases postoperative pain scores and narcotic medication requirements [1-3]. However, there is limited information on the techniques for preemptive analgesia [4,5]. DESIGN: An instructional video showing a variety of preemptive analgesia techniques and the corresponding neuroanatomy (Canadian Task Force classification III). Mayo Clinic Institutional Review Board approval was not required for this video article. SETTING: Academic Medical Center INTERVENTIONS: Relevant abdominopelvic neuroanatomy is reviewed. This is followed by a demonstration of the preemptive analgesia techniques based on neuroanatomy principles. CONCLUSION: Techniques for preemptive analgesia are simple and effective. These tools can be used for patients undergoing gynecologic surgeries via a vaginal or abdominal approach and can help optimize postoperative pain and narcotic usage.


Assuntos
Analgesia/métodos , Procedimentos Cirúrgicos em Ginecologia , Dor Pós-Operatória/prevenção & controle , Assistência Perioperatória/métodos , Analgésicos/uso terapêutico , Feminino , Humanos , Manejo da Dor , Medição da Dor , Dor Pós-Operatória/diagnóstico , Dor Pós-Operatória/tratamento farmacológico
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