Detalhe da pesquisa
1.
Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound.
Proc Natl Acad Sci U S A
; 120(28): e2219543120, 2023 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37406092
2.
Neutral sphingomyelinase 2 is required for HIV-1 maturation.
Proc Natl Acad Sci U S A
; 120(28): e2219475120, 2023 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37406093
3.
Neuronal deletion of nSMase2 reduces the production of Aß and directly protects neurons.
Neurobiol Dis
; 177: 105987, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36603748
4.
Physiological Exploration of the Long Term Evolutionary Selection against Expression of N-Glycolylneuraminic Acid in the Brain.
J Biol Chem
; 292(7): 2557-2570, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049733
5.
Sialylation regulates brain structure and function.
FASEB J
; 29(7): 3040-53, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25846372
6.
Ganglioside regulation of AMPA receptor trafficking.
J Neurosci
; 34(39): 13246-58, 2014 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25253868
7.
Immune following suppression mesenchymal stem cell transplantation in the ischemic brain is mediated by TGF-ß.
Neurobiol Dis
; 58: 249-57, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23759293
8.
Discovery of Orally Bioavailable and Brain-Penetrable Prodrugs of the Potent nSMase2 Inhibitor DPTIP.
J Med Chem
; 65(16): 11111-11125, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35930706
9.
Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice.
Pharmaceutics
; 14(10)2022 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36297501
10.
Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury.
Biochem Pharmacol
; 194: 114796, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34678224
11.
The growth of brain tumors can be suppressed by multiple transplantation of mesenchymal stem cells expressing cytosine deaminase.
Int J Cancer
; 127(8): 1975-83, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20473873
12.
MEAnalyzer - a Spike Train Analysis Tool for Multi Electrode Arrays.
Neuroinformatics
; 18(1): 163-179, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31273627
13.
Inhibition of neutral sphingomyelinase 2 promotes remyelination.
Sci Adv
; 6(40)2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33008902
14.
Astrocytes deliver CK1 to neurons via extracellular vesicles in response to inflammation promoting the translation and amyloidogenic processing of APP.
J Extracell Vesicles
; 10(2): e12035, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33408815
15.
Neural induction with neurogenin1 increases the therapeutic effects of mesenchymal stem cells in the ischemic brain.
Stem Cells
; 26(9): 2217-28, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18617687
16.
A novel and potent brain penetrant inhibitor of extracellular vesicle release.
Br J Pharmacol
; 176(19): 3857-3870, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31273753
17.
Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model.
Exp Mol Med
; 40(4): 387-97, 2008 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-18779651
18.
Spatiotemporal Protein Atlas of Cell Death-Related Molecules in the Rat MCAO Stroke Model.
Exp Neurobiol
; 27(4): 287-298, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-30181691
19.
TNFα and IL-1ß modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons.
Cell Death Dis
; 9(3): 363, 2018 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29507357
20.
Pharmacokinetics of Intranasal versus Subcutaneous Insulin in the Mouse.
ACS Chem Neurosci
; 9(4): 809-816, 2018 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29257872