Detalhe da pesquisa
1.
The discovery and structure-activity relationships of pyrano[3,4-b]indole-based inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 21(11): 3227-31, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21550237
2.
The discovery and structure-activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 20(9): 2968-73, 2010 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20347591
3.
Molecular mechanism of hepatitis C virus replicon variants with reduced susceptibility to a benzofuran inhibitor, HCV-796.
Antimicrob Agents Chemother
; 52(9): 3327-38, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18559648
4.
Predicting breast cancer risk: implications of a "weak" family history.
Fam Cancer
; 7(4): 361-6, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18560993
5.
Analysis of referrals to a multi-disciplinary breast cancer genetics clinic: practical and economic considerations.
Fam Cancer
; 5(4): 297-303, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16819594
6.
Design, expression, and purification of a Flaviviridae polymerase using a high-throughput approach to facilitate crystal structure determination.
Protein Sci
; 13(10): 2685-92, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15388860
7.
Newly synthesized hepatitis C virus replicon RNA is protected from nuclease activity by a protease-sensitive factor(s).
J Virol
; 78(18): 10202-5, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15331754
8.
The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation.
Proc Natl Acad Sci U S A
; 101(13): 4425-30, 2004 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-15070734
9.
Novel nonnucleoside inhibitor of hepatitis C virus RNA-dependent RNA polymerase.
Antimicrob Agents Chemother
; 48(12): 4813-21, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15561861
10.
The discovery of pyrano[3,4-b]indole-based allosteric inhibitors of HCV NS5B polymerase with in vivo activity.
ChemMedChem
; 3(10): 1508-15, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18729128