Detalhe da pesquisa
1.
Novel RNA molecular bioengineering technology efficiently produces functional miRNA agents.
RNA
; 30(6): 680-694, 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38429100
2.
The Growing Class of Novel RNAi Therapeutics.
Mol Pharmacol
; 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38719476
3.
RNAi-Based Therapeutics and Novel RNA Bioengineering Technologies.
J Pharmacol Exp Ther
; 384(1): 133-154, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35680378
4.
Recombinant Technologies Facilitate Drug Metabolism, Pharmacokinetics, and General Biomedical Research.
Drug Metab Dispos
; 51(6): 685-699, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36948592
5.
RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges.
Pharmacol Rev
; 72(4): 862-898, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32929000
6.
Nuclear receptor RORγ inverse agonists/antagonists display tissue- and gene-context selectivity through distinct activities in altering chromatin accessibility and master regulator SREBP2 occupancy.
Pharmacol Res
; 182: 106324, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35750301
7.
A Novel Integrated Pharmacokinetic-Pharmacodynamic Model to Evaluate Combination Therapy and Determine In Vivo Synergism.
J Pharmacol Exp Ther
; 377(3): 305-315, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33712506
8.
MicroRNA-1291-5p Sensitizes Pancreatic Carcinoma Cells to Arginine Deprivation and Chemotherapy through the Regulation of Arginolysis and Glycolysis.
Mol Pharmacol
; 98(6): 686-694, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33051382
9.
Pharmacokinetic and Pharmacodynamic Factors Contribute to Synergism between Let-7c-5p and 5-Fluorouracil in Inhibiting Hepatocellular Carcinoma Cell Viability.
Drug Metab Dispos
; 48(12): 1257-1263, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33051247
10.
Novel approaches for efficient in vivo fermentation production of noncoding RNAs.
Appl Microbiol Biotechnol
; 104(5): 1927-1937, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31953559
11.
The HMOX1 Pathway as a Promising Target for the Treatment and Prevention of SARS-CoV-2 of 2019 (COVID-19).
Int J Mol Sci
; 21(17)2020 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32899231
12.
Bioengineering of a single long noncoding RNA molecule that carries multiple small RNAs.
Appl Microbiol Biotechnol
; 103(15): 6107-6117, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31187211
13.
Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy.
J Pharmacol Exp Ther
; 365(3): 494-506, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29602831
14.
Bioengineered NRF2-siRNA Is Effective to Interfere with NRF2 Pathways and Improve Chemosensitivity of Human Cancer Cells.
Drug Metab Dispos
; 46(1): 2-10, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29061583
15.
PPARα regulates tumor cell proliferation and senescence via a novel target gene carnitine palmitoyltransferase 1C.
Carcinogenesis
; 38(4): 474-483, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334197
16.
Effects of MicroRNA-34a on the Pharmacokinetics of Cytochrome P450 Probe Drugs in Mice.
Drug Metab Dispos
; 45(5): 512-522, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28254952
17.
A general approach to high-yield biosynthesis of chimeric RNAs bearing various types of functional small RNAs for broad applications.
Nucleic Acids Res
; 43(7): 3857-69, 2015 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25800741
18.
Comparing early liver graft function from heart beating and living-donors: A pilot study aiming to identify new biomarkers of liver injury.
Biopharm Drug Dispos
; 38(5): 326-339, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28102538
19.
MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy.
Drug Metab Dispos
; 44(3): 308-19, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26566807
20.
Altered expression of small heterodimer partner governs cytochrome P450 (CYP) 2D6 induction during pregnancy in CYP2D6-humanized mice.
J Biol Chem
; 289(6): 3105-13, 2014 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24318876