Detalhe da pesquisa
1.
The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer.
Mol Cell
; 69(1): 87-99.e7, 2018 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29249655
2.
Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment.
Nature
; 539(7628): 304-308, 2016 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27783593
3.
Targeting HIF-1α in combination with PPARα activation and postnatal factors promotes the metabolic maturation of human induced pluripotent stem cell-derived cardiomyocytes.
J Mol Cell Cardiol
; 132: 120-135, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31082397
4.
Maintenance of mouse hematopoietic stem cells ex vivo by reprogramming cellular metabolism.
Blood
; 125(10): 1562-5, 2015 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25593337
5.
Cited2, a transcriptional modulator protein, regulates metabolism in murine embryonic stem cells.
J Biol Chem
; 289(1): 251-63, 2014 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24265312
6.
AMPK activator-treated human cardiac spheres enhance maturation and enable pathological modeling.
Stem Cell Res Ther
; 14(1): 322, 2023 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37941041
7.
A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells.
Blood
; 116(18): 3611-21, 2010 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-20651068
8.
Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and Biomechanics.
Cell Stem Cell
; 24(4): 608-620.e6, 2019 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30880025
9.
Critical role of ASCT2-mediated amino acid metabolism in promoting leukaemia development and progression.
Nat Metab
; 1(3): 390-403, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31535081
10.
Hematopoietic-restricted Ptpn11E76K reveals indolent MPN progression in mice.
Oncotarget
; 9(31): 21831-21843, 2018 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29774106
11.
Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner.
Sci Signal
; 11(522)2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29559584
12.
Mitochondrial oxidation of the carbohydrate fuel is required for neural precursor/stem cell function and postnatal cerebellar development.
Sci Adv
; 4(10): eaat2681, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30338292
13.
Factor XII and uPAR upregulate neutrophil functions to influence wound healing.
J Clin Invest
; 128(3): 944-959, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29376892
14.
Shp-2 tyrosine phosphatase is required for hepatocyte growth factor-induced activation of sphingosine kinase and migration in embryonic fibroblasts.
Cell Signal
; 18(11): 2049-55, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16765027
15.
Synergistic cell death in FLT3-ITD positive acute myeloid leukemia by combined treatment with metformin and 6-benzylthioinosine.
Leuk Res
; 50: 132-140, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27760406
16.
A negative role of SHP-2 tyrosine phosphatase in growth factor-dependent hematopoietic cell survival.
Oncogene
; 23(20): 3659-69, 2004 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-15116097
17.
Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling.
Oncogene
; 22(38): 5995-6004, 2003 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-12955078
18.
Surveillance and control of post-transmission schistosomiasis in Jiaxing prefecture, Zhejiang province, China.
Acta Trop
; 96(2-3): 282-7, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16198300
19.
Increased numbers of committed myeloid progenitors but not primitive hematopoietic stem/progenitors in mice lacking STAT6 expression.
J Leukoc Biol
; 76(2): 484-90, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15123777
20.
Activating mutations in protein tyrosine phosphatase Ptpn11 (Shp2) enhance reactive oxygen species production that contributes to myeloproliferative disorder.
PLoS One
; 8(5): e63152, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23675459