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1.
Sensors (Basel) ; 20(5)2020 Mar 10.
Artigo em Inglês | MEDLINE | ID: mdl-32164282

RESUMO

Since the revival of multiferroic laminates with giant magnetoelectric (ME) coefficients, a variety of multifunctional ME devices, such as sensor, inductor, filter, antenna etc. have been developed. Magnetoelastic materials, which couple the magnetization and strain together, have recently attracted ever-increasing attention due to their key roles in ME applications. This review starts with a brief introduction to the early research efforts in the field of multiferroic materials and moves to the recent work on magnetoelectric coupling and their applications based on both bulk and thin-film materials. This is followed by sections summarizing historical works and solving the challenges specific to the fabrication and characterization of magnetoelastic materials with large magnetostriction constants. After presenting the magnetostrictive thin films and their static and dynamic properties, we review micro-electromechanical systems (MEMS) and bulk devices utilizing ME effect. Finally, some open questions and future application directions where the community could head for magnetoelastic materials will be discussed.

2.
J Neural Eng ; 20(1)2023 01 18.
Artigo em Inglês | MEDLINE | ID: mdl-36651596

RESUMO

Objective. Noninvasive focal stimulation of deep brain regions has been a major goal for neuroscience and neuromodulation in the past three decades. Transcranial magnetic stimulation (TMS), for instance, cannot target deep regions in the brain without activating the overlying tissues and has poor spatial resolution. In this manuscript, we propose a new concept that relies on the temporal interference (TI) of two high-frequency magnetic fields generated by two electromagnetic solenoids.Approach. To illustrate the concept, custom solenoids were fabricated and optimized to generate temporal interfering electric fields for rodent brain stimulation. C-Fos expression was used to track neuronal activation.Main result. C-Fos expression was not present in regions impacted by only one high-frequency magnetic field indicating ineffective recruitment of neural activity in non-target regions. In contrast, regions impacted by two fields that interfere to create a low-frequency envelope display a strong increase in c-Fos expression.Significance. Therefore, this magnetic temporal interference solenoid-based system provides a framework to perform further stimulation studies that would investigate the advantages it could bring over conventional TMS systems.


Assuntos
Encéfalo , Estimulação Magnética Transcraniana , Encéfalo/fisiologia , Campos Magnéticos , Técnicas Estereotáxicas , Neurônios/fisiologia , Campos Eletromagnéticos
3.
IEEE Open J Circuits Syst ; 4: 139-155, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37829556

RESUMO

A magnetoelectric antenna (ME) can exhibit the dual capabilities of wireless energy harvesting and sensing at different frequencies. In this article, a behavioral circuit model for hybrid ME antennas is described to emulate the radio frequency (RF) energy harvesting and sensing operations during circuit simulations. The ME antenna of this work is interfaced with a CMOS energy harvester chip towards the goal of developing a wireless communication link for fully integrated implantable devices. One role of the integrated system is to receive pulse-modulated power from a nearby transmitter, and another role is to sense and transmit low-magnitude neural signals. The measurements reported in this paper are the first results that demonstrate simultaneous low-frequency wireless magnetic sensing and high-frequency wireless energy harvesting at two different frequencies with one dual-mode ME antenna. The proposed behavioral ME antenna model can be utilized during design optimizations of energy harvesting circuits. Measurements were performed to validate the wireless power transfer link with an ME antenna having a 2.57 GHz resonance frequency connected to an energy harvester chip designed in 65nm CMOS technology. Furthermore, this dual-mode ME antenna enables concurrent sensing using a carrier signal with a frequency that matches the second 63.63 MHz resonance mode. A wireless test platform has been developed for evaluation of ME antennas as a tool for neural implant design, and this prototype system was utilized to provide first experimental results with the transmission of magnetically modulated action potential waveforms.

4.
Microsyst Nanoeng ; 7: 91, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34786205

RESUMO

Electrical stimulation via invasive microelectrodes is commonly used to treat a wide range of neurological and psychiatric conditions. Despite its remarkable success, the stimulation performance is not sustainable since the electrodes become encapsulated by gliosis due to foreign body reactions. Magnetic stimulation overcomes these limitations by eliminating the need for a metal-electrode contact. Here, we demonstrate a novel microfabricated solenoid inductor (80 µm × 40 µm) with a magnetic core that can activate neuronal tissue. The characterization and proof-of-concept of the device raise the possibility that micromagnetic stimulation solenoids that are small enough to be implanted within the brain may prove to be an effective alternative to existing electrode-based stimulation devices for chronic neural interfacing applications.

5.
Annu Int Conf IEEE Eng Med Biol Soc ; 2021: 6167-6170, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-34892524

RESUMO

A novel magnetoelectric (ME) antenna is fabricated to be integrated to the on-chip energy harvesting circuit for brain-computer interface applications. The proposed ME antenna resonates at the frequency of 2.57 GHz while providing a bandwidth of 3.37 MHz. The proposed rectangular ME antenna wireless power transfer efficiency is 0.304 %, which is considerably higher than that of micro-coils.Clinical Relevance- This provides a suitable energy harvesting efficiency for wirelessly powering up the brain implant devices.


Assuntos
Interfaces Cérebro-Computador , Tecnologia sem Fio , Próteses e Implantes
6.
Adv Mater Technol ; 6(9)2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35558167

RESUMO

Miniaturized piezoelectric/magnetostrictive contour-mode resonators have been shown to be effective magnetometers by exploiting the ΔE effect. With dimensions of ~100-200 µm across and <1 µm thick, they offer high spatial resolution, portability, low power consumption, and low cost. However, a thorough understanding of the magnetic material behavior in these devices has been lacking, hindering performance optimization. This manuscript reports on the strong, nonlinear correlation observed between the frequency response of these sensors and the stress-induced curvature of the resonator plate. The resonance frequency shift caused by DC magnetic fields drops off rapidly with increasing curvature: about two orders of magnitude separate the highest and lowest frequency shift in otherwise identical devices. Similarly, an inverse correlation with the quality factor was found, suggesting a magnetic loss mechanism. The mechanical and magnetic properties are theoretically analyzed using magnetoelastic finite-element and magnetic domain-phase models. The resulting model fits the measurements well and is generally consistent with additional results from magneto-optical domain imaging. Thus, the origin of the observed behavior is identified and broader implications for the design of nano-magnetoelastic devices are derived. By fabricating a magnetoelectric nano-plate resonator with low curvature, a record-high DC magnetic field sensitivity of 5 Hz/nT is achieved.

7.
Nat Commun ; 12(1): 3141, 2021 05 25.
Artigo em Inglês | MEDLINE | ID: mdl-34035237

RESUMO

Ultra-compact wireless implantable medical devices are in great demand for healthcare applications, in particular for neural recording and stimulation. Current implantable technologies based on miniaturized micro-coils suffer from low wireless power transfer efficiency (PTE) and are not always compliant with the specific absorption rate imposed by the Federal Communications Commission. Moreover, current implantable devices are reliant on differential recording of voltage or current across space and require direct contact between electrode and tissue. Here, we show an ultra-compact dual-band smart nanoelectromechanical systems magnetoelectric (ME) antenna with a size of 250 × 174 µm2 that can efficiently perform wireless energy harvesting and sense ultra-small magnetic fields. The proposed ME antenna has a wireless PTE 1-2 orders of magnitude higher than any other reported miniaturized micro-coil, allowing the wireless IMDs to be compliant with the SAR limit. Furthermore, the antenna's magnetic field detectivity of 300-500 pT allows the IMDs to record neural magnetic fields.


Assuntos
Eletrodos Implantados , Nanotecnologia/instrumentação , Tecnologia sem Fio/instrumentação , Animais , Desenho de Equipamento , Campos Magnéticos , Camundongos , Modelos Animais , Ratos , Materiais Inteligentes
8.
Analog Integr Circuits Signal Process ; 105(3): 407-415, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34511725

RESUMO

A low-noise amplifier (LNA) topology with tunable input matching and noise cancellation is introduced and described in this paper, which was designed and optimized to interface with a magnetoelectric (ME) antenna in a 0.35 µm MEMS-compatible CMOS process. Compared to conventional antennas, acoustically actuated ME antennas have significantly smaller area for ease of integration. The LNA was simulated with an ME antenna model that was constructed based on antenna measurements. Input matching at the LNA-antenna interface is controlled with a circuit that varies the effective impedance of the gate inductor using a control voltage. Tunability of 455 MHz around 2.4 GHz is achieved for the optimum S11 frequency with a control voltage range of 0.3 V to 1.2 V. The proposed LNA has a noise cancelling feedback loop that improves the noise figure by 4.1 dB. The post-layout simulation results of the LNA show a 1-dB compression point of -7.4 dBm with an S21 of 17.8 dB.

9.
Annu Int Conf IEEE Eng Med Biol Soc ; 2018: 2230-2233, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30440849

RESUMO

Magnetic stimulation using micro-coils has shown to be an effective method for brain neural modulation [1]. These micro-coils could arguably be superior to commonly used micro-electrodes in terms of long-term functionality. This is because, unlike electrode based devices, magnetic coils do not need to have direct contact with brain tissues and thus their efficiency and stimulation capability do not degrade overtime. In this study, we compare three different micro-coils and show that the use of magnetic-core in the inductors could substantially improve the coil's performance and help to generate more than 13 times stronger electric field and electric field gradient.


Assuntos
Magnetismo , Encéfalo , Estimulação Magnética Transcraniana
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