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1.
Eur Respir J ; 39(2): 344-51, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21737563

RESUMO

Hiatal hernia (HH) is associated with gastro-oesophageal reflux (GOR) and/or GOR disease and may contribute to idiopathic pulmonary fibrosis (IPF). We hypothesised that HH evaluated by computed tomography is more common in IPF than in asthma or chronic obstructive pulmonary disease (COPD), and correlates with abnormal GOR measured by pH probe testing. Rates of HH were compared in three cohorts, IPF (n=100), COPD (n=60) and asthma (n=24), and evaluated for inter-observer agreement. In IPF, symptoms and anti-reflux medications were correlated with diffusing capacity of the lung for carbon monoxide (D(L,CO)) and composite physiologic index (CPI). HH was correlated with pH probe testing in IPF patients (n=14). HH was higher in IPF (39%) than either COPD (13.3%, p=0.00009) or asthma (16.67%, p=0.0139). The HH inter-observer κ agreement was substantial in IPF (κ=0.78) and asthma (κ=0.86), and moderate in COPD (κ=0.42). In IPF, HH did not correlate with lung function, except in those on anti-reflux therapy, who had a better D(L,CO) (p<0.03) and CPI (p<0.04). HH correlated with GOR as measured by DeMeester scores (p<0.04). HH is more common in IPF than COPD or asthma. In an IPF cohort, HH correlated with higher DeMeester scores, confirming abnormal acid GOR. Presence of HH alone was not associated with decreased lung function.


Assuntos
Hérnia Hiatal/diagnóstico por imagem , Hérnia Hiatal/epidemiologia , Fibrose Pulmonar Idiopática/diagnóstico por imagem , Fibrose Pulmonar Idiopática/epidemiologia , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Adulto , Idoso , Asma/diagnóstico por imagem , Asma/epidemiologia , Estudos de Coortes , Feminino , Refluxo Gastroesofágico/diagnóstico por imagem , Refluxo Gastroesofágico/epidemiologia , Refluxo Gastroesofágico/terapia , Humanos , Concentração de Íons de Hidrogênio , Doenças Pulmonares Intersticiais/diagnóstico por imagem , Doenças Pulmonares Intersticiais/epidemiologia , Masculino , Manometria , Pessoa de Meia-Idade , Variações Dependentes do Observador , Prevalência , Doença Pulmonar Obstrutiva Crônica/diagnóstico por imagem , Doença Pulmonar Obstrutiva Crônica/epidemiologia , Estudos Retrospectivos , Índice de Gravidade de Doença
2.
J Vasc Access ; 8(4): 228-30, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-18161666

RESUMO

Though rare, dialysis associated steal syndrome (DASS) can cause debilitating symptoms. Surgical revision of the dialysis access is typically required. We describe a percutaneous technique to alleviate steal syndrome utilizing a constrained stent within an arteriovenous graft. A brief review of the incidence, pathophysiology, and standard treatment of DASS is also provided.


Assuntos
Angioplastia com Balão/instrumentação , Braço/irrigação sanguínea , Derivação Arteriovenosa Cirúrgica/efeitos adversos , Implante de Prótese Vascular/efeitos adversos , Isquemia/terapia , Diálise Renal , Stents , Veia Axilar/cirurgia , Artéria Braquial/cirurgia , Feminino , Humanos , Isquemia/diagnóstico por imagem , Isquemia/etiologia , Pessoa de Meia-Idade , Radiografia , Resultado do Tratamento
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