Detalhe da pesquisa
1.
Skeletal muscle insulin resistance is induced by 4-hydroxy-2-hexenal, a by-product of n-3 fatty acid peroxidation.
Diabetologia
; 61(3): 688-699, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29299636
2.
Glucose and fatty acids synergistically and reversibly promote beta cell proliferation in rats.
Diabetologia
; 60(5): 879-888, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28078385
3.
Per-Arnt-Sim kinase regulates pancreatic duodenal homeobox-1 protein stability via phosphorylation of glycogen synthase kinase 3ß in pancreatic ß-cells.
J Biol Chem
; 288(34): 24825-33, 2013 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23853095
4.
Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis.
Aging (Albany NY)
; 15(12): 5240-5265, 2023 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37341993
5.
Chronotherapy with a glucokinase activator profoundly improves metabolism in obese Zucker rats.
Sci Transl Med
; 14(668): eabh1316, 2022 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36288279
6.
Discovery by Virtual Screening of an Inhibitor of CDK5-Mediated PPARγ Phosphorylation.
ACS Med Chem Lett
; 13(4): 681-686, 2022 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35450368
7.
Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes.
Sci Adv
; 8(46): eadd5430, 2022 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36383675
8.
Glucolipotoxicity of the pancreatic beta cell.
Biochim Biophys Acta
; 1801(3): 289-98, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19715772
9.
Human uremic plasma and not urea induces exuberant secretion of leptin in 3T3-L1 adipocytes.
J Ren Nutr
; 21(1): 72-5, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21195924
10.
An Obesogenic Dietary Mouse Model of Nonalcoholic Steatohepatitis.
Methods Mol Biol
; 2164: 121-127, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32607889
11.
Lou/C obesity-resistant rat exhibits hyperactivity, hypermetabolism, alterations in white adipose tissue cellularity, and lipid tissue profiles.
Endocrinology
; 149(2): 615-25, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18006635
12.
The regulator of G-protein signaling RGS16 promotes insulin secretion and ß-cell proliferation in rodent and human islets.
Mol Metab
; 5(10): 988-996, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27689011
13.
The ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Is Associated With Progressive Insulin Resistance and Decreased Functional ß-Cell Mass in Mice.
Diabetes
; 64(12): 4112-22, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26283735
14.
Ozone exposure triggers insulin resistance through muscle c-Jun N-terminal kinase activation.
Diabetes
; 64(3): 1011-24, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25277399
15.
Pancreatic and duodenal homeobox-1 nuclear localization is regulated by glucose in dispersed rat islets but not in insulin-secreting cell lines.
Islets
; 6(4): e982376, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25437380
16.
Epidermal growth factor receptor signaling promotes pancreatic ß-cell proliferation in response to nutrient excess in rats through mTOR and FOXM1.
Diabetes
; 63(3): 982-93, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24194502
17.
The islet estrogen receptor-α is induced by hyperglycemia and protects against oxidative stress-induced insulin-deficient diabetes.
PLoS One
; 9(2): e87941, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24498408
18.
A model of chronic nutrient infusion in the rat.
J Vis Exp
; (78)2013 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23979115
19.
Npas4 is a novel activity-regulated cytoprotective factor in pancreatic ß-cells.
Diabetes
; 62(8): 2808-20, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23656887
20.
Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass.
Diabetes
; 59(9): 2178-87, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20547980