Detalhe da pesquisa
1.
Cytokine-like Roles for Metabolites in Immunity.
Mol Cell
; 78(5): 814-823, 2020 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32333837
2.
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Nature
; 556(7699): 113-117, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29590092
3.
4-Octyl-Itaconate and Dimethyl Fumarate Inhibit COX2 Expression and Prostaglandin Production in Macrophages.
J Immunol
; 207(10): 2561-2569, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34635585
4.
The Trypanosome-Derived Metabolite Indole-3-Pyruvate Inhibits Prostaglandin Production in Macrophages by Targeting COX2.
J Immunol
; 207(10): 2551-2560, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34635586
5.
Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma.
Int J Mol Sci
; 24(5)2023 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36902148
6.
Resident alveolar macrophage-derived vesicular SOCS3 dampens allergic airway inflammation.
FASEB J
; 34(3): 4718-4731, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32030817
7.
Circadian clock protein BMAL1 regulates IL-1ß in macrophages via NRF2.
Proc Natl Acad Sci U S A
; 115(36): E8460-E8468, 2018 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30127006
8.
Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increase Systemic Inflammation and Cardiovascular Disease.
Circ Res
; 122(6): 855-863, 2018 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29437834
9.
Specific Inhibition of the NLRP3 Inflammasome as an Antiinflammatory Strategy in Cystic Fibrosis.
Am J Respir Crit Care Med
; 200(11): 1381-1391, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31454256
10.
An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation.
J Biol Chem
; 293(15): 5509-5521, 2018 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29463677
11.
The Induction of Pro-IL-1ß by Lipopolysaccharide Requires Endogenous Prostaglandin E2 Production.
J Immunol
; 198(9): 3558-3564, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28298525
12.
The circadian protein BMAL1 in myeloid cells is a negative regulator of allergic asthma.
Am J Physiol Lung Cell Mol Physiol
; 312(6): L855-L860, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28336811
13.
Protein kinase A inhibition of macrophage maturation is accompanied by an increase in DNA methylation of the colony-stimulating factor 1 receptor gene.
Immunology
; 149(2): 225-37, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27353657
14.
Resident alveolar macrophages suppress, whereas recruited monocytes promote, allergic lung inflammation in murine models of asthma.
J Immunol
; 193(8): 4245-53, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25225663
15.
Inhibition of protein translation as a novel mechanism for prostaglandin E2 regulation of cell functions.
FASEB J
; 28(1): 56-66, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24072780
16.
Prostaglandin E2 suppresses allergic sensitization and lung inflammation by targeting the E prostanoid 2 receptor on T cells.
J Allergy Clin Immunol
; 133(2): 379-87, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24075232
17.
Prostaglandin E2 reduces Toll-like receptor 4 expression in alveolar macrophages by inhibition of translation.
Am J Respir Cell Mol Biol
; 51(2): 242-50, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24601788
18.
Prostaglandin E2 restrains macrophage maturation via E prostanoid receptor 2/protein kinase A signaling.
Blood
; 119(10): 2358-67, 2012 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22234697
19.
Metabolism-driven glycosylation represents therapeutic opportunities in interstitial lung diseases.
Front Immunol
; 15: 1328781, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38550597
20.
The Exploitation of the Glycosylation Pattern in Asthma: How We Alter Ancestral Pathways to Develop New Treatments.
Biomolecules
; 14(5)2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38785919