Detalhe da pesquisa
1.
Fluorine and chlorine substituted adamantyl-urea as molecular tools for inhibition of human soluble epoxide hydrolase with picomolar efficacy.
J Enzyme Inhib Med Chem
; 38(1): 2274797, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37975322
2.
Novel substituted 5-methyl-4-acylaminoisoxazoles as antimitotic agents: Evaluation of selectivity to LNCaP cancer cells.
Arch Pharm (Weinheim)
; 355(5): e2100425, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35103336
3.
Bicyclic Isoxazoline Derivatives: Synthesis and Evaluation of Biological Activity.
Molecules
; 27(11)2022 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35684482
4.
Tick-borne flavivirus reproduction inhibitors based on isoxazole core linked with adamantane.
Bioorg Chem
; 87: 629-637, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30947098
5.
Novel antimitotic agents related to tubuloclustin: synthesis and biological evaluation.
Mol Divers
; 21(3): 547-564, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28484934
6.
Unusual tubulin-clustering ability of specifically c7-modified colchicine analogues.
Chembiochem
; 14(12): 1444-9, 2013 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23843347
7.
Verubulin (Azixa) Analogues with Increased Saturation: Synthesis, SAR and Encapsulation in Biocompatible Nanocontainers Based on Ca2+ or Mg2+ Cross-Linked Alginate.
Pharmaceuticals (Basel)
; 16(10)2023 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37895970
8.
Synthesis and SAR requirements of adamantane-colchicine conjugates with both microtubule depolymerizing and tubulin clustering activities.
Bioorg Med Chem
; 19(18): 5529-38, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21873068
9.
Application of the bridgehead fragments for the design of conformationally restricted melatonin analogues.
Bioorg Chem
; 39(2): 67-72, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21419469
10.
Design, synthesis, and bioactivity of putative tubulin ligands with adamantane core.
Bioorg Med Chem Lett
; 18(18): 5091-4, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18715782