Detalhe da pesquisa
1.
Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40.
Nat Immunol
; 20(10): 1322-1334, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31427773
2.
NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Nat Immunol
; 17(3): 250-8, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26642356
3.
RNPS1 inhibits excessive tumor necrosis factor/tumor necrosis factor receptor signaling to support hematopoiesis in mice.
Proc Natl Acad Sci U S A
; 119(18): e2200128119, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35482923
4.
Thousands of induced germline mutations affecting immune cells identified by automated meiotic mapping coupled with machine learning.
Proc Natl Acad Sci U S A
; 118(28)2021 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34260399
5.
Essential requirement for nicastrin in marginal zone and B-1 B cell development.
Proc Natl Acad Sci U S A
; 117(9): 4894-4901, 2020 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32071239
6.
Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.
Proc Natl Acad Sci U S A
; 117(15): 8563-8572, 2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32220963
7.
Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice.
Proc Natl Acad Sci U S A
; 116(23): 11380-11389, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31097594
8.
Dominant atopy risk mutations identified by mouse forward genetic analysis.
Allergy
; 76(4): 1095-1108, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32810290
9.
Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice.
Proc Natl Acad Sci U S A
; 115(37): E8698-E8706, 2018 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30150374
10.
Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function.
Proc Natl Acad Sci U S A
; 115(49): E11523-E11531, 2018 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30442666
11.
A proteomic approach identifies SAFB-like transcription modulator (SLTM) as a bidirectional regulator of GLI family zinc finger transcription factors.
J Biol Chem
; 294(14): 5549-5561, 2019 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30782847
12.
Creatine maintains intestinal homeostasis and protects against colitis.
Proc Natl Acad Sci U S A
; 114(7): E1273-E1281, 2017 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28137860
13.
Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5.
Proc Natl Acad Sci U S A
; 114(26): E5197-E5206, 2017 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607088
14.
IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice.
Proc Natl Acad Sci U S A
; 114(7): E1196-E1204, 2017 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28137874
15.
Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.
Proc Natl Acad Sci U S A
; 113(42): E6418-E6426, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27708159
16.
TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc Natl Acad Sci U S A
; 113(7): E884-93, 2016 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26831104
17.
Mutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infection.
Proc Natl Acad Sci U S A
; 112(42): E5706-14, 2015 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26438836
18.
Real-time resolution of point mutations that cause phenovariance in mice.
Proc Natl Acad Sci U S A
; 112(5): E440-9, 2015 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25605905
19.
Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling.
Proc Natl Acad Sci U S A
; 111(20): 7367-72, 2014 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24799716
20.
Generation of BAF53b-Cre transgenic mice with pan-neuronal Cre activities.
Genesis
; 53(7): 440-8, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26077106