Detalhe da pesquisa
1.
The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo.
Cell
; 151(4): 900-911, 2012 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23141545
2.
Correlation of antigen expression with epigenetic modifications after rAAV delivery of a human factor IX variant in mice and rhesus macaques.
Mol Ther
; 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38715361
3.
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals.
Nat Methods
; 17(8): 852-860, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32661427
4.
A transfer-RNA-derived small RNA regulates ribosome biogenesis.
Nature
; 552(7683): 57-62, 2017 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29186115
5.
Improved Genome Editing through Inhibition of FANCM and Members of the BTR Dissolvase Complex.
Mol Ther
; 29(3): 1016-1027, 2021 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33678249
6.
Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.
Mol Ther
; 26(1): 289-303, 2018 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29055620
7.
Sequence-Modified Antibiotic Resistance Genes Provide Sustained Plasmid-Mediated Transgene Expression in Mammals.
Mol Ther
; 25(5): 1187-1198, 2017 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28365028
8.
Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs.
Nucleic Acids Res
; 42(19): 12169-76, 2014 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25270879
9.
A mini-intronic plasmid (MIP): a novel robust transgene expression vector in vivo and in vitro.
Mol Ther
; 21(5): 954-63, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23459514
10.
Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes.
Proc Natl Acad Sci U S A
; 108(22): 9208-13, 2011 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-21576459
11.
AAV-mediated genome editing is influenced by the formation of R-loops.
bioRxiv
; 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38766176
12.
The extragenic spacer length between the 5' and 3' ends of the transgene expression cassette affects transgene silencing from plasmid-based vectors.
Mol Ther
; 20(11): 2111-9, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22565847
13.
Ribosomal DNA integrating rAAV-rDNA vectors allow for stable transgene expression.
Mol Ther
; 20(10): 1912-23, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22990671
14.
Aptamer-programmable adeno-associated viral vectors as a novel platform for cell-specific gene transfer.
Mol Ther Nucleic Acids
; 31: 383-397, 2023 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36817723
15.
The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner.
Nat Commun
; 14(1): 2448, 2023 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37117181
16.
Selection of rAAV vectors that cross the human blood-brain barrier and target the central nervous system using a transwell model.
Mol Ther Methods Clin Dev
; 27: 73-88, 2022 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36186955
17.
Fludarabine increases nuclease-free AAV- and CRISPR/Cas9-mediated homologous recombination in mice.
Nat Biotechnol
; 40(8): 1285-1294, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35393561
18.
Toxicity Identification Evaluation of Sediments from the Xihe River.
Environ Toxicol Chem
; 40(11): 3103-3110, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34344060
19.
Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors.
JCI Insight
; 4(22)2019 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31723052
20.
miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression.
Nat Commun
; 9(1): 5321, 2018 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30552326