Detalhe da pesquisa
1.
FASN negatively regulates p65 expression by reducing its stability via Thr254 phosphorylation and isomerization by Pin1.
J Lipid Res
; 65(4): 100529, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38467328
2.
eIF3d: A driver of noncanonical cap-dependent translation of specific mRNAs and a trigger of biological/pathological processes.
J Biol Chem
; 299(5): 104658, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36997088
3.
Translation initiation factor eIF3a regulates glucose metabolism and cell proliferation via promoting small GTPase Rheb synthesis and AMPK activation.
J Biol Chem
; 298(7): 102044, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35595099
4.
Proton Pump Inhibitor Use and Obesity-Associated Cancer in the Women's Health Initiative.
Nutr Cancer
; 75(1): 265-275, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-35968582
5.
APC Loss Prevents Doxorubicin-Induced Cell Death by Increasing Drug Efflux and a Chemoresistant Cell Population in Breast Cancer.
Int J Mol Sci
; 24(8)2023 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37108784
6.
A novel survivin dimerization inhibitor without a labile hydrazone linker induces spontaneous apoptosis and synergizes with docetaxel in prostate cancer cells.
Bioorg Med Chem
; 65: 116761, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35504208
7.
Ginsenoside Rh2 inhibits breast cancer cell growth via ERß-TNFα pathway.
Acta Biochim Biophys Sin (Shanghai)
; 54(5): 647-656, 2022 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35593465
8.
Translational regulation of Chk1 expression by eIF3a via interaction with the RNA-binding protein HuR.
Biochem J
; 477(10): 1939-1950, 2020 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32391557
9.
Single-nucleotide polymorphisms in a short basic motif in the ABC transporter ABCG2 disable its trafficking out of endoplasmic reticulum and reduce cell resistance to anticancer drugs.
J Biol Chem
; 294(52): 20222-20232, 2019 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31719146
10.
Dual Functional Modification of Alkaline Amino Acids Induces the Self-Assembly of Cylinder-Like Tobacco Mosaic Virus Coat Proteins into Gear-Like Architectures.
Small
; 15(10): e1805543, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30706634
11.
CC-115, a Dual Mammalian Target of Rapamycin/DNA-Dependent Protein Kinase Inhibitor in Clinical Trial, Is a Substrate of ATP-Binding Cassette G2, a Risk Factor for CC-115 Resistance.
J Pharmacol Exp Ther
; 371(2): 320-326, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31455631
12.
FASN regulates cellular response to genotoxic treatments by increasing PARP-1 expression and DNA repair activity via NF-κB and SP1.
Proc Natl Acad Sci U S A
; 113(45): E6965-E6973, 2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791122
13.
Corrigendum to "A novel survivin dimerization inhibitor without a labile hydrazone linker induces spontaneous apoptosis and synergizes with docetaxel in prostate cancer cells" [Bioorg. Med. Chem. 65 (2022) 116761].
Bioorg Med Chem
; 78: 117127, 2023 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36517371
14.
Reversible epigenetic regulation of 14-3-3σ expression in acquired gemcitabine resistance by uhrf1 and DNA methyltransferase 1.
Mol Pharmacol
; 86(5): 561-9, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25189999
15.
Spectrin domain of eukaryotic initiation factor 3a is the docking site for formation of the a:b:i:g subcomplex.
J Biol Chem
; 288(39): 27951-9, 2013 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23921387
16.
Determinants of 14-3-3σ protein dimerization and function in drug and radiation resistance.
J Biol Chem
; 288(44): 31447-57, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24043626
17.
Smart exosomes enhance PDAC targeted therapy.
J Control Release
; 368: 413-429, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38431093
18.
Fatty acid synthase causes drug resistance by inhibiting TNF-α and ceramide production.
J Lipid Res
; 54(3): 776-785, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23319743
19.
Translational regulation of RPA2 via internal ribosomal entry site and by eIF3a.
Carcinogenesis
; 34(6): 1224-31, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23393223
20.
Small Molecule Inhibitors Targeting the "Undruggable" Survivin: The Past, Present, and Future from a Medicinal Chemist's Perspective.
J Med Chem
; 66(24): 16515-16545, 2023 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38092421