Detalhe da pesquisa
1.
Oncofetal SNRPE promotes HCC tumorigenesis by regulating the FGFR4 expression through alternative splicing.
Br J Cancer
; 2024 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38796598
2.
CHIR-98014, a GSK 3ß Inhibitor, Protects Against Triptolide/Lipopolysaccharide-Induced Hepatotoxicity by Mitochondria-Dependent Apoptosis Inhibition.
Chem Res Toxicol
; 37(2): 407-418, 2024 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38284557
3.
Discovery of LH10, a novel fexaramine-based FXR agonist for the treatment of liver disease.
Bioorg Chem
; 143: 107071, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38199141
4.
Tetrahedral framework nucleic acids for improving wound healing.
J Nanobiotechnology
; 22(1): 113, 2024 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38491372
5.
Group 1 innate lymphoid cell activation via recognition of NKG2D and liver resident macrophage MULT-1: Collaborated roles in triptolide induced hepatic immunotoxicity in mice.
Ecotoxicol Environ Saf
; 272: 116072, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38342011
6.
Targeting Moonlighting Enzymes in Cancer.
Molecules
; 29(7)2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38611852
7.
8-methoxypsoralen protects against acetaminophen-induced liver injury by antagonising Cyp2e1 in mice.
Arch Biochem Biophys
; 741: 109617, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37121295
8.
Activation of cDCs and iNKT cells contributes to triptolide-induced hepatotoxicity via STING signaling pathway and endoplasmic reticulum stress.
Cell Biol Toxicol
; 39(4): 1753-1772, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36520315
9.
Design, synthesis, and biological evaluation studies of novel carboxylesterase 2 inhibitors for the treatment of irinotecan-induced delayed diarrhea.
Bioorg Chem
; 138: 106625, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37300962
10.
iNKT17 cells play a pathogenic role in ethinylestradiol-induced cholestatic hepatotoxicity.
Arch Toxicol
; 97(2): 561-580, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36329302
11.
Hyperoside ameliorates cisplatin-induced acute kidney injury by regulating the expression and function of Oat1.
Xenobiotica
; 53(8-9): 559-571, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37885225
12.
Obeticholic acid improved triptolide/lipopolysaccharide-induced hepatotoxicity by inhibiting caspase-11-GSDMD pyroptosis pathway.
J Appl Toxicol
; 43(4): 599-614, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36328986
13.
Correction: Li et al. Shikonin Attenuates Acetaminophen-Induced Hepatotoxicity by Upregulation of Nrf2 through Akt/GSK3ß Signaling. Molecules 2019, 24, 110.
Molecules
; 28(14)2023 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37513493
14.
Design, synthesis, and biological evaluation of novel dual FFA1 and PPARδ agonists possessing phenoxyacetic acid scaffold.
Bioorg Med Chem
; 56: 116615, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35051813
15.
Design, synthesis, and biological studies of dual URAT1 inhibitor and FXR agonist based on benzbromarone.
Bioorg Med Chem
; 75: 117073, 2022 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36347120
16.
Design, synthesis and biological evaluation studies of novel anti-fibrosis agents bearing sulfoxide moiety.
Bioorg Med Chem
; 75: 117096, 2022 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36395681
17.
The key role of organic anion transporter 3 in the drug-drug interaction between tranilast and methotrexate.
J Biochem Mol Toxicol
; 36(4): e22983, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35019195
18.
Tetramethylpyrazine prevents liver fibrotic injury in mice by targeting hepatocyte-derived and mitochondrial DNA-enriched extracellular vesicles.
Acta Pharmacol Sin
; 43(8): 2026-2041, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35027662
19.
[Determination of concentrations and toxicokinetics of triptolide in plasma and liver of mice by UHPLC-MS/MS].
Zhongguo Zhong Yao Za Zhi
; 47(15): 4183-4189, 2022 Aug.
Artigo
em Zh
| MEDLINE | ID: mdl-36046909
20.
SEW2871 attenuates ANIT-induced hepatotoxicity by protecting liver barrier function via sphingosine 1-phosphate receptor-1-mediated AMPK signaling pathway.
Cell Biol Toxicol
; 37(4): 595-609, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33400020