Detalhe da pesquisa
1.
The interplay of protein engineering and glycoengineering to fine-tune antibody glycosylation and its impact on effector functions.
Biotechnol Bioeng
; 119(1): 102-117, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34647616
2.
Appropriate aglycone modification significantly expands the glycan substrate acceptability of α1,6-fucosyltransferase (FUT8).
Biochem J
; 478(8): 1571-1583, 2021 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33734311
3.
One-Pot Conversion of Free Sialoglycans to Functionalized Glycan Oxazolines and Efficient Synthesis of Homogeneous Antibody-Drug Conjugates through Site-Specific Chemoenzymatic Glycan Remodeling.
Bioconjug Chem
; 32(8): 1888-1897, 2021 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34351736
4.
Comparative studies on the substrate specificity and defucosylation activity of three α-l-fucosidases using synthetic fucosylated glycopeptides and glycoproteins as substrates.
Bioorg Med Chem
; 42: 116243, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34126284
5.
Chemoenzymatic Synthesis and Antibody Binding of HIV-1 V1/V2 Glycopeptide-Bacteriophage Qß Conjugates as a Vaccine Candidate.
Int J Mol Sci
; 22(22)2021 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34830420
6.
Revisiting the substrate specificity of mammalian α1,6-fucosyltransferase reveals that it catalyzes core fucosylation of N-glycans lacking α1,3-arm GlcNAc.
J Biol Chem
; 292(36): 14796-14803, 2017 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28729420
7.
Chemically Controlled Epigenome Editing through an Inducible dCas9 System.
J Am Chem Soc
; 139(33): 11337-11340, 2017 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28787145
8.
Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with ß subunits.
bioRxiv
; 2024 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38328192
9.
An intranasally administrated SARS-CoV-2 beta variant subunit booster vaccine prevents beta variant replication in rhesus macaques.
PNAS Nexus
; 1(3): pgac091, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35873792
10.
A facile chemoenzymatic synthesis of SARS-CoV-2 glycopeptides for probing glycosylation functions.
Chem Commun (Camb)
; 57(55): 6804-6807, 2021 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34236361
11.
Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques.
JCI Insight
; 6(10)2021 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33908897
12.
Multivalent Antigen Presentation Enhances the Immunogenicity of a Synthetic Three-Component HIV-1 V3 Glycopeptide Vaccine.
ACS Cent Sci
; 4(5): 582-589, 2018 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29806004
13.
Synthetic HIV V3 Glycopeptide Immunogen Carrying a N334 N-Glycan Induces Glycan-Dependent Antibodies with Promiscuous Site Recognition.
J Med Chem
; 61(22): 10116-10125, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30384610
14.
Engineering Iron Responses in Mammalian Cells by Signal-Induced Protein Proximity.
ACS Synth Biol
; 6(6): 921-927, 2017 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28221778
15.
Glycan Remodeling of Human Erythropoietin (EPO) Through Combined Mammalian Cell Engineering and Chemoenzymatic Transglycosylation.
ACS Chem Biol
; 12(6): 1665-1673, 2017 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28452462
16.
Synthetic Three-Component HIV-1 V3 Glycopeptide Immunogens Induce Glycan-Dependent Antibody Responses.
Cell Chem Biol
; 24(12): 1513-1522.e4, 2017 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29107699
17.
Constructing de novo H2O2 signaling via induced protein proximity.
ACS Chem Biol
; 10(6): 1404-10, 2015 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25775006