Detalhe da pesquisa
1.
CDK7-dependent transcriptional addiction in triple-negative breast cancer.
Cell
; 163(1): 174-86, 2015 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26406377
2.
PI3Kß controls immune evasion in PTEN-deficient breast tumours.
Nature
; 617(7959): 139-146, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37076617
3.
Lactate regulates cell cycle by remodelling the anaphase promoting complex.
Nature
; 616(7958): 790-797, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36921622
4.
PI3Kγ maintains the self-renewal of acute myeloid leukemia stem cells by regulating the pentose phosphate pathway.
Blood
; 143(19): 1965-1979, 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38271660
5.
Targeting oncogenic KRAS with molecular brush-conjugated antisense oligonucleotides.
Proc Natl Acad Sci U S A
; 119(29): e2113180119, 2022 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35858356
6.
Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma.
Nature
; 549(7673): 533-537, 2017 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28959975
7.
CDK4/6 inhibition triggers anti-tumour immunity.
Nature
; 548(7668): 471-475, 2017 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28813415
8.
PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition.
Proc Natl Acad Sci U S A
; 117(39): 24427-24433, 2020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32929011
9.
Maximizing TLR9 Activation in Cancer Immunotherapy with Dual-Adjuvanted Spherical Nucleic Acids.
Nano Lett
; 22(10): 4058-4066, 2022 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35522597
10.
Targeted profiling of RNA translation reveals mTOR-4EBP1/2-independent translation regulation of mRNAs encoding ribosomal proteins.
Proc Natl Acad Sci U S A
; 115(40): E9325-E9332, 2018 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30224479
11.
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation.
Proc Natl Acad Sci U S A
; 115(41): E9600-E9609, 2018 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30254159
12.
Spatially distinct roles of class Ia PI3K isoforms in the development and maintenance of PTEN hamartoma tumor syndrome.
Genes Dev
; 27(14): 1568-80, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23873941
13.
The emerging role of PI3K/AKT-mediated epigenetic regulation in cancer.
Biochim Biophys Acta Rev Cancer
; 1868(1): 123-131, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28315368
14.
PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α.
Proc Natl Acad Sci U S A
; 114(27): 7095-7100, 2017 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28630349
15.
The p110α and p110ß isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis.
Genes Dev
; 26(14): 1573-86, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22802530
16.
Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor.
Proc Natl Acad Sci U S A
; 113(46): 13156-13161, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27799550
17.
Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival.
Proc Natl Acad Sci U S A
; 113(35): 9810-5, 2016 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27528663
18.
Corrigendum: Essential roles of PI(3)K-p110ß in cell growth, metabolism and tumorigenesis.
Nature
; 533(7602): 278, 2016 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26814969
19.
PI3K isoform dependence of PTEN-deficient tumors can be altered by the genetic context.
Proc Natl Acad Sci U S A
; 111(17): 6395-400, 2014 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24737887
20.
Chemopreventive effects of aspirin at a glance.
Biochim Biophys Acta
; 1855(2): 254-63, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25842298