Detalhe da pesquisa
1.
Preclinical evaluation of a brain penetrant PARP PET imaging probe in rat glioblastoma and nonhuman primates.
Eur J Nucl Med Mol Imaging
; 50(7): 2081-2099, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36849748
2.
Age, gender and body-mass-index relationships with in vivo CB1 receptor availability in healthy humans measured with [11C]OMAR PET.
Neuroimage
; 264: 119674, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36243269
3.
A metabolically stable PET tracer for imaging synaptic vesicle protein 2A: synthesis and preclinical characterization of [18F]SDM-16.
Eur J Nucl Med Mol Imaging
; 49(5): 1482-1496, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34761284
4.
Feasibility study of PET dynamic imaging of [18F]DHMT for quantification of reactive oxygen species in the myocardium of large animals.
J Nucl Cardiol
; 29(1): 216-225, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32415628
5.
Preliminary In Vivo Evidence of Reduced Synaptic Density in Human Immunodeficiency Virus (HIV) Despite Antiretroviral Therapy.
Clin Infect Dis
; 73(8): 1404-1411, 2021 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050746
6.
Separating dopamine D2 and D3 receptor sources of [11C]-(+)-PHNO binding potential: Independent component analysis of competitive binding.
Neuroimage
; 214: 116762, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32201327
7.
Novel Kappa Opioid Receptor Agonist as Improved PET Radiotracer: Development and in Vivo Evaluation.
Mol Pharm
; 16(4): 1523-1531, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30726092
8.
PET imaging of α7 nicotinic acetylcholine receptors: a comparative study of [18F]ASEM and [18F]DBT-10 in nonhuman primates, and further evaluation of [18F]ASEM in humans.
Eur J Nucl Med Mol Imaging
; 44(6): 1042-1050, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28120003
9.
Receptor Occupancy of the κ-Opioid Antagonist LY2456302 Measured with Positron Emission Tomography and the Novel Radiotracer 11C-LY2795050.
J Pharmacol Exp Ther
; 356(2): 260-6, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26628406
10.
PET imaging evaluation of [(18)F]DBT-10, a novel radioligand specific to α7 nicotinic acetylcholine receptors, in nonhuman primates.
Eur J Nucl Med Mol Imaging
; 43(3): 537-47, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26455500
11.
Comparative evaluation of two glycine transporter 1 radiotracers [11C]GSK931145 and [18F]MK-6577 in baboons.
Synapse
; 70(3): 112-20, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26671330
12.
Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma.
Proc Natl Acad Sci U S A
; 110(29): 11751-6, 2013 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23818631
13.
A Promising PET Tracer for Imaging of α7 Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand.
Molecules
; 20(10): 18387-421, 2015 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26473809
14.
Evaluation of the agonist PET radioligand [¹¹C]GR103545 to image kappa opioid receptor in humans: kinetic model selection, test-retest reproducibility and receptor occupancy by the antagonist PF-04455242.
Neuroimage
; 99: 69-79, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24844744
15.
Radiolabeling of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with biotinylated F-18 prosthetic groups and imaging of their delivery to the brain with positron emission tomography.
Bioconjug Chem
; 25(12): 2157-65, 2014 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25322194
16.
Evaluation of the sensitivity of the novel α4ß2* nicotinic acetylcholine receptor PET radioligand 18F-(-)-NCFHEB to increases in synaptic acetylcholine levels in rhesus monkeys.
Synapse
; 68(11): 556-64, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25043426
17.
PET Imaging of Sphingosine-1-Phosphate Receptor 1 with [18F]TZ4877 in Nonhuman Primates.
Res Sq
; 2024 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38854065
18.
Test-retest reproducibility of [11C]-(+)-propyl-hexahydro-naphtho-oxazin positron emission tomography using the bolus plus constant infusion paradigm.
Mol Imaging
; 12(2): 77-82, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23415395
19.
In Vivo Imaging and Kinetic Modeling of Novel Glycogen Synthase Kinase-3 Radiotracers [11C]OCM-44 and [18F]OCM-50 in Non-Human Primates.
Pharmaceuticals (Basel)
; 16(2)2023 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37259346
20.
Cholinergic system adaptations are associated with cognitive function in people recently abstinent from smoking: a (-)-[18F]flubatine PET study.
Neuropsychopharmacology
; 48(4): 683-689, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36681758