Detalhe da pesquisa
1.
Antiviral activity of aframomum melegueta against severe acute respiratory syndrome coronaviruses type 1 and 2.
S Afr J Bot
; 146: 735-739, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-34955582
2.
Griffithsin and Carrageenan Combination Results in Antiviral Synergy against SARS-CoV-1 and 2 in a Pseudoviral Model.
Mar Drugs
; 19(8)2021 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34436255
3.
In Vitro Exposure to PC-1005 and Cervicovaginal Lavage Fluid from Women Vaginally Administered PC-1005 Inhibits HIV-1 and HSV-2 Infection in Human Cervical Mucosa.
Antimicrob Agents Chemother
; 60(9): 5459-66, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27381393
4.
Multipurpose Prevention Approaches with Antiretroviral-Based Formulations.
Antimicrob Agents Chemother
; 60(2): 1141-4, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26596943
5.
MIV-150/zinc acetate gel inhibits cell-associated simian-human immunodeficiency virus reverse transcriptase infection in a macaque vaginal explant model.
Antimicrob Agents Chemother
; 59(7): 3829-37, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25870063
6.
Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human Papillomavirus.
Antimicrob Agents Chemother
; 59(12): 7290-8, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26369967
7.
MIV-150-containing intravaginal rings protect macaque vaginal explants against SHIV-RT infection.
Antimicrob Agents Chemother
; 58(5): 2841-8, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24614384
8.
A modified zinc acetate gel, a potential nonantiretroviral microbicide, is safe and effective against simian-human immunodeficiency virus and herpes simplex virus 2 infection in vivo.
Antimicrob Agents Chemother
; 57(8): 4001-9, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23752515
9.
Zinc acetate/carrageenan gels exhibit potent activity in vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge.
Antimicrob Agents Chemother
; 56(1): 358-68, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22064530
10.
Results of a phase 1, randomized, placebo-controlled first-in-human trial of griffithsin formulated in a carrageenan vaginal gel.
PLoS One
; 17(1): e0261775, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35051209
11.
Validation of a dye stain assay for vaginally inserted hydroxyethylcellulose-filled microbicide applicators.
Sex Transm Dis
; 38(11): 1050-5, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21992983
12.
Griffithsin carrageenan fast dissolving inserts prevent SHIV HSV-2 and HPV infections in vivo.
Nat Commun
; 9(1): 3881, 2018 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30250170
13.
MIV-150 and zinc acetate combination provides potent and broad activity against HIV-1.
Drug Deliv Transl Res
; 7(6): 859-866, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28812250
14.
MZC Gel Inhibits SHIV-RT and HSV-2 in Macaque Vaginal Mucosa and SHIV-RT in Rectal Mucosa.
J Acquir Immune Defic Syndr
; 74(3): e67-e74, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27552154
15.
An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques.
Drug Deliv Transl Res
; 7(6): 840-858, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28600625
16.
First-in-Human Trial of MIV-150 and Zinc Acetate Coformulated in a Carrageenan Gel: Safety, Pharmacokinetics, Acceptability, Adherence, and Pharmacodynamics.
J Acquir Immune Defic Syndr
; 73(5): 489-496, 2016 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27437826
17.
A Novel Microbicide/Contraceptive Intravaginal Ring Protects Macaque Genital Mucosa against SHIV-RT Infection Ex Vivo.
PLoS One
; 11(7): e0159332, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27428377
18.
Taking the daily grind out of HIV prevention.
EBioMedicine
; 59: 102934, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32810819
19.
Preclinical assessments of vaginal microbicide candidate safety and efficacy.
Adv Drug Deliv Rev
; 92: 27-38, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25543007
20.
A novel intravaginal ring to prevent HIV-1, HSV-2, HPV, and unintended pregnancy.
J Control Release
; 213: 57-68, 2015 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26091920