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1.
Surgery ; 142(1): 33-9, 2007 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-17629998

RESUMO

BACKGROUND: Roux Stasis Syndrome is a well-known complication after Roux-en-Y reconstruction. It has been hypothesized that reconstruction with an uncut Roux limb and jejunal pouch after total gastrectomy would preserve unidirectional intestinal myoelectrical activity, improve postoperative weight gain and nutritional parameters, and diminish Roux Stasis Syndrome in canines. METHODS: A total gastrectomy was performed, and 2 methods were used for reconstruction: Roux-en-Y esophagojejunostomy (RY) was performed on 5 canines (control), and the uncut Roux-en-Y with a jejunal pouch (URYJP) was performed on 5 other canines (experimental). The canines were monitored for 10 weeks postoperatively. Serial weight and nutritional parameters were measured. Emptying profiles and motility studies were performed in the fasting and postprandial states. RESULTS: Ten weeks after operation, the URYJP group had significantly improved nutritional parameters, including weight, total protein, albumin, hemoglobin, serum total iron binding capacity, and serum IgA, IgG, and IgM. The emptying times for both groups were similar, with an increase of disordered propagation of the jejunal pacesetter potential in the RY group. The aboral propagation occurred more frequently in the URYJP group during fasting and after feeding (98% +/- 1% vs 39% +/- 16%; P = .02, and 99% +/- 1% vs 43% +/- 18%; P = .03). The sites of luminal occlusions were intact in the URYJP group at 10 weeks. CONCLUSIONS: The combination of jejunal pouch and uncut Roux limb improved overall nutritional parameters when compared with the traditional Roux-en-Y, while preserving aboral propagation of jejunal pacesetter potentials.


Assuntos
Anastomose em-Y de Roux , Gastrectomia/métodos , Jejuno/cirurgia , Estruturas Criadas Cirurgicamente , Animais , Cães , Eletrofisiologia , Esofagostomia , Jejum , Feminino , Esvaziamento Gástrico , Sistema Imunitário/fisiopatologia , Jejunostomia , Jejuno/fisiopatologia , Músculo Liso/fisiopatologia , Estado Nutricional , Período Pós-Prandial
2.
J Obstet Gynaecol ; 24(7): 750-5, 2004 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-15763780

RESUMO

A case - control study was conducted to assess the risk factors of stillbirth among pregnant women in Jamaica. A total of 314 women participated (160 with stillborn babies and 154 with live-born babies). A questionnaire designed to collect information on sociodemographic characteristics, antenatal care, medical and sexually transmitted disease (STD) history, method of delivery and infant birth and health status was administered to each woman. Medical records were reviewed to verify medical history. Six variables were found to be significant predictors of stillbirth by multivariate logistic regression. Low birth weight (OR = 4.3, CI = 2.4 - 7.7), complications during pregnancy or delivery (OR = .19, CI = 0.09 - 0.41), method of delivery (caesarean section; OR = 7.2, CI = 1.6 - 33.2), number of living children (OR = 0.54, CI = 0.40 - 0.73), number of antenatal visits (less than three; OR = 2.0, CI = 1.3 - 3.1), and presence of unfavourable and /or adverse fetal outcome (OR = 4.0, CI = 1.8 - 9.2) were found to be associated with stillbirth. These findings have important implications in establishing policies for prenatal care in Jamaica.


Assuntos
Resultado da Gravidez/epidemiologia , Adulto , Peso ao Nascer , Cesárea , Escolaridade , Feminino , Idade Gestacional , Humanos , Jamaica/epidemiologia , Modelos Logísticos , Estado Civil , Complicações do Trabalho de Parto , Gravidez , Complicações na Gravidez , Cuidado Pré-Natal , Fatores de Risco
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