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Genotype distribution of the GB virus C in citizens of Säo Paulo City, Brazil
Nishiya, Anna S; Ribeiro-dos-Santos, Gabriela; Bassit, Leda; Focaccia, Roberto; Chamone, Dalton F; Sabino, Ester C.
Affiliation
  • Nishiya, Anna S; Fundaçäo Pró-Sangue. Hemocentro de Säo Paulo. Säo Paulo. BR
  • Ribeiro-dos-Santos, Gabriela; Fundaçäo Pró-Sangue. Hemocentro de Säo Paulo. Säo Paulo. BR
  • Bassit, Leda; Fundaçäo Pró-Sangue. Hemocentro de Säo Paulo. Säo Paulo. BR
  • Focaccia, Roberto; Institute of Infectology Emílio Ribas. Säo Paulo. BR
  • Chamone, Dalton F; Fundaçäo Pró-Sangue. Hemocentro de Säo Paulo. Säo Paulo. BR
  • Sabino, Ester C; Fundaçäo Pró-Sangue. Hemocentro de Säo Paulo. Säo Paulo. BR
Rev. Inst. Med. Trop. Säo Paulo ; Rev. Inst. Med. Trop. Säo Paulo;45(4): 213-216, July-Aug. 2003. ilus
Article in En | LILACS, SES-SP | ID: lil-345385
Responsible library: BR1.1
ABSTRACT
There has been several studies worldwide on phylogenetics and genotype distribution of the GB-virus C / Hepatitis G virus (GBV-C/HGV). However, in their great majority, those investigations were based on some epidemiologically linked group, rather than on a representative sampling of the general population. The present is a continuation of the first study in Brazil with such a population; it addresses the GBV-C/HGV phylogenetics and genotype distribution based on samples identified among more than 1,000 individuals of the city of Säo Paulo. For this purpose, a 728 bp fragment of the 5 non-coding region (5 NCR) of the viral genome, from 24 isolates, was sequenced and subjected to phylogenetic analysis. Genotypes 1, 2a and 2b were found at 8.3 percent (2/24), 50 percent (12/24) and 41.7 percent (10/24), respectively. In conclusion Säo Paulo displays a genotype distribution similar to the published data for other States and Regions of Brazil, endorsing the notion that types 1 and 2 would have entered the country with African and European people, respectively, since its earliest formation
Subject(s)
Full text: 1 Database: LILACS Main subject: Phylogeny / RNA, Viral / Flaviviridae / 5' Untranslated Regions Limits: Humans Country/Region as subject: America do sul / Brasil Language: En Journal: Rev. Inst. Med. Trop. Säo Paulo Journal subject: MEDICINA TROPICAL Year: 2003 Type: Article / Project document Affiliation country: Brazil
Full text: 1 Database: LILACS Main subject: Phylogeny / RNA, Viral / Flaviviridae / 5' Untranslated Regions Limits: Humans Country/Region as subject: America do sul / Brasil Language: En Journal: Rev. Inst. Med. Trop. Säo Paulo Journal subject: MEDICINA TROPICAL Year: 2003 Type: Article / Project document Affiliation country: Brazil