Genotype distribution of the GB virus C in citizens of Säo Paulo City, Brazil
Rev. Inst. Med. Trop. Säo Paulo
; Rev. Inst. Med. Trop. Säo Paulo;45(4): 213-216, July-Aug. 2003. ilus
Article
in En
| LILACS, SES-SP
| ID: lil-345385
Responsible library:
BR1.1
ABSTRACT
There has been several studies worldwide on phylogenetics and genotype distribution of the GB-virus C / Hepatitis G virus (GBV-C/HGV). However, in their great majority, those investigations were based on some epidemiologically linked group, rather than on a representative sampling of the general population. The present is a continuation of the first study in Brazil with such a population; it addresses the GBV-C/HGV phylogenetics and genotype distribution based on samples identified among more than 1,000 individuals of the city of Säo Paulo. For this purpose, a 728 bp fragment of the 5 non-coding region (5 NCR) of the viral genome, from 24 isolates, was sequenced and subjected to phylogenetic analysis. Genotypes 1, 2a and 2b were found at 8.3 percent (2/24), 50 percent (12/24) and 41.7 percent (10/24), respectively. In conclusion Säo Paulo displays a genotype distribution similar to the published data for other States and Regions of Brazil, endorsing the notion that types 1 and 2 would have entered the country with African and European people, respectively, since its earliest formation
Full text:
1
Database:
LILACS
Main subject:
Phylogeny
/
RNA, Viral
/
Flaviviridae
/
5' Untranslated Regions
Limits:
Humans
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Rev. Inst. Med. Trop. Säo Paulo
Journal subject:
MEDICINA TROPICAL
Year:
2003
Type:
Article
/
Project document
Affiliation country:
Brazil