Embriopatía por isotretinoína: Un daño evitable / Isotretinoin embryophaty: Report of one case
Rev. méd. Chile
; 136(6): 763-766, jun. 2008. ilus
Article
in Es
| LILACS
| ID: lil-490763
Responsible library:
BR1.1
ABSTRACT
Retinoic acid is a widely used drug in the treatment of cystic acné. It has teratogenic effects that depend on the gestational period in which it is used. We report a seven months of female whose mother was exposed to retinoic acid in both pregestational and gestational periods. She had a retardation of psychomotor development and a brain MRI showed frontal atrophy and a malformation of the posterior fossa. We discuss the mechanisms ofthe teratogenic effeets of retinoic acid.
Key words
Full text:
1
Database:
LILACS
Main subject:
Teratogens
/
Abnormalities, Drug-Induced
/
Abnormalities, Multiple
/
Isotretinoin
/
Craniofacial Abnormalities
/
Keratolytic Agents
Limits:
Female
/
Humans
/
Infant
/
Pregnancy
Language:
Es
Journal:
Rev. méd. Chile
Journal subject:
MEDICINA
Year:
2008
Type:
Article
Affiliation country:
Chile