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Prefrontal damage in childhood and changes in the development of personality: a case report / Dano pré-frontal na infância e alterações no desenvolvimento da personalidade: um relato de caso
Bahia, Valéria Santoro; Takada, Leonel Tadao; Caixeta, Leonardo; Lucato, Leandro Tavares; Porto, Claudia Sellitto; Nitrini, Ricardo.
Affiliation
  • Bahia, Valéria Santoro; University of São Paulo School of Medicine. Hospital das Clínicas. Department of Neurology. Behavioral and Cognitive Neurology Unit. São Paulo SP. BR
  • Takada, Leonel Tadao; University of São Paulo School of Medicine. Hospital das Clínicas. Department of Neurology. Behavioral and Cognitive Neurology Unit. São Paulo SP. BR
  • Caixeta, Leonardo; Federal University of Goiás. Goiânia GO. BR
  • Lucato, Leandro Tavares; Universidade de São Paulo. Faculdade de Medicina. Hospital das Clínicas. Instituto de Radiologia. Centro de Diagnósticos Brasil. São Paulo SP. BR
  • Porto, Claudia Sellitto; University of São Paulo School of Medicine. Hospital das Clínicas. Department of Neurology. Behavioral and Cognitive Neurology Unit. São Paulo SP. BR
  • Nitrini, Ricardo; University of São Paulo School of Medicine. Hospital das Clínicas. Department of Neurology. Behavioral and Cognitive Neurology Unit. São Paulo SP. BR
Dement. neuropsychol ; 7(1): 132-135, jan.-mar. 2013. ilus
Article in En | LILACS | ID: lil-670741
Responsible library: BR15.3
Localization: BR15.3
ABSTRACT
Frontal lobe lesions are associated with behavioral abnormalities and executive dysfunction. When these lesions occur early in life, the symptoms are even more severe as the anatomical and functional substrates underlying personality and behavior are damaged, distorting normal modulation by interaction with the psychosocial environment. We present a case of a 40-year-old man who suffered a frontal lobe lesion at the age of nine years and developed impulsivity, disinhibition and inappropriate behaviors while showing some preservation of insight. Brain MRI revealed lesions to bilateral orbitofrontal cortex, ventromedial prefrontal cortex, anterior cingulate gyri and genu of the corpus callosum, which were more extensive on the right side. The right prefrontal dorsolateral cortex was severely damaged, whereas the right ventrolateral prefrontal cortex was spared. We will discuss the correlation of the damaged pre frontal regions with the symptoms presented by the patient.
RESUMO
Lesões no lobo frontal são associadas com sintomas de distúrbios do comportamento e disfunção executiva. Quando a lesão ocorre em fase precoce da vida, os sintomas são ainda mais intensos pois o substrato anatômico e funcional da formação da personalidade e comportamento está danificado, então, a sua modulação decorrente da interação com o meio psicossocial será distorcida. Apresentamos aqui o caso de um homem de 40 anos que sofreu uma lesão no lobo frontal aos nove anos de idade, com sintomas de impulsividade com manutenção parcial da autocrítica, desinibição e comportamento inapropriado. A ressonância de crânio evidenciava lesões bilaterais do córtex orbitofrontal da porção anterior do giro do cíngulo e do joelho do corpo caloso e do córtex ventromedial, mais extensa à direita. O córtex pré-frontal dorsolateral estava extensamente acometido à direita, enquanto o córtex pré-frontal ventrolateral parecia poupado. Discutiremos a correlação das áreas pré frontais lesadas com a sintomatologia do paciente.
Subject(s)
Key words
Full text: 1 Database: LILACS Main subject: Social Behavior / Brain Injuries, Traumatic / Frontal Lobe / Neuropsychology Limits: Humans Language: En Journal: Dement. neuropsychol Journal subject: NEUROCIENCIAS / NEUROLOGIA / PSICOLOGIA / PSIQUIATRIA Year: 2013 Type: Article Affiliation country: Brazil
Full text: 1 Database: LILACS Main subject: Social Behavior / Brain Injuries, Traumatic / Frontal Lobe / Neuropsychology Limits: Humans Language: En Journal: Dement. neuropsychol Journal subject: NEUROCIENCIAS / NEUROLOGIA / PSICOLOGIA / PSIQUIATRIA Year: 2013 Type: Article Affiliation country: Brazil