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Pityriasis lichenoides-like mycosis fungoides in children.
Ko, J W; Seong, J Y; Suh, K S; Kim, S T.
Affiliation
  • Ko JW; Department of Dermatology, Kosin Medical Center, Pusan, South Korea.
Br J Dermatol ; 142(2): 347-52, 2000 Feb.
Article in En | MEDLINE | ID: mdl-10730773
We report three children with clinical features of pityriasis lichenoides (scaly red to brown papules and macules) in whom there were histopathological findings of mycosis fungoides (disproportionate epidermotropism, Pautrier's microabscesses, and wiry and coarse collagen bundles). Immunohistochemical staining revealed a prevalence of T lymphocytes in the infiltrate. T-cell receptor gene rearrangement analysis in lesional skin demonstrated rearrangement of the gamma chain in all cases. Human T-cell lymphotropic virus type 1 serology was negative in the two patients in whom this test was performed. Thus, lesions resembling pityriasis lichenoides can be an unusual and potentially misleading presentation of mycosis fungoides.
Subject(s)
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Database: MEDLINE Main subject: Skin Neoplasms / Mycosis Fungoides / Pityriasis Lichenoides Type of study: Diagnostic_studies / Risk_factors_studies Limits: Child / Child, preschool / Humans / Male Language: En Journal: Br J Dermatol Year: 2000 Type: Article Affiliation country: Korea (South)
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Database: MEDLINE Main subject: Skin Neoplasms / Mycosis Fungoides / Pityriasis Lichenoides Type of study: Diagnostic_studies / Risk_factors_studies Limits: Child / Child, preschool / Humans / Male Language: En Journal: Br J Dermatol Year: 2000 Type: Article Affiliation country: Korea (South)