Therapeutic efficacy of the suicide gene driven by the promoter of vascular endothelial growth factor gene against hypoxic tumor cells.

Koshikawa, N; Takenaga, K; Tagawa, M; Sakiyama, S

Koshikawa, N; Takenaga, K; Tagawa, M; Sakiyama, S.

Affiliation

Koshikawa N; Division of Pathology, Chiba Cancer Center Research Institute, Japan.

Cancer Res ; 60(11): 2936-41, 2000 Jun 01.

Article in En | MEDLINE | ID: mdl-10850440

Subject(s)

Endothelial Growth Factors/genetics; Hypoxia; Lymphokines/genetics; Promoter Regions, Genetic; Simplexvirus/genetics; Thymidine Kinase/genetics; Animals; Antiviral Agents/pharmacology; Blotting, Northern; Carcinoma, Lewis Lung/genetics; Cloning, Molecular; Dose-Response Relationship, Drug; Ganciclovir/pharmacology; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Luminescent Proteins/metabolism; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Plasmids; RNA, Messenger/metabolism; Sequence Analysis, DNA; Simplexvirus/enzymology; Time Factors; Transfection; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

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Database: MEDLINE Main subject: Thymidine Kinase / Endothelial Growth Factors / Lymphokines / Promoter Regions, Genetic / Simplexvirus / Hypoxia Limits: Animals Language: En Journal: Cancer Res Year: 2000 Type: Article Affiliation country: Japan

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