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Oxidative stress increases MICA and MICB gene expression in the human colon carcinoma cell line (CaCo-2).
Yamamoto, K; Fujiyama, Y; Andoh, A; Bamba, T; Okabe, H.
Affiliation
  • Yamamoto K; Department of Clinical Laboratory Medicine, Shiga University of Medical Science, Otsu, Japan. yamak@belle.shiga-med.ac.jp
Biochim Biophys Acta ; 1526(1): 10-2, 2001 Apr 03.
Article in En | MEDLINE | ID: mdl-11287116
ABSTRACT
The human major histocompatibility complex class I chain-related A gene (MICA) and the MICB gene are newly identified members of the major histocompatibility complex class I chain-related gene family. We demonstrate here that oxidative stress, induced by H(2)O(2), promoted MICA (2.2-fold) and MICB (3.8-fold) gene expression using the human colon carcinoma cell line (CaCo-2) and semi-quantitative RT-PCR.
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Database: MEDLINE Main subject: Histocompatibility Antigens Class I / Oxidative Stress / Caco-2 Cells / Membrane Proteins Limits: Humans Language: En Journal: Biochim Biophys Acta Year: 2001 Type: Article Affiliation country: Japan
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Database: MEDLINE Main subject: Histocompatibility Antigens Class I / Oxidative Stress / Caco-2 Cells / Membrane Proteins Limits: Humans Language: En Journal: Biochim Biophys Acta Year: 2001 Type: Article Affiliation country: Japan