Oxidative stress increases MICA and MICB gene expression in the human colon carcinoma cell line (CaCo-2).
Biochim Biophys Acta
; 1526(1): 10-2, 2001 Apr 03.
Article
in En
| MEDLINE
| ID: mdl-11287116
ABSTRACT
The human major histocompatibility complex class I chain-related A gene (MICA) and the MICB gene are newly identified members of the major histocompatibility complex class I chain-related gene family. We demonstrate here that oxidative stress, induced by H(2)O(2), promoted MICA (2.2-fold) and MICB (3.8-fold) gene expression using the human colon carcinoma cell line (CaCo-2) and semi-quantitative RT-PCR.
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Database:
MEDLINE
Main subject:
Histocompatibility Antigens Class I
/
Oxidative Stress
/
Caco-2 Cells
/
Membrane Proteins
Limits:
Humans
Language:
En
Journal:
Biochim Biophys Acta
Year:
2001
Type:
Article
Affiliation country:
Japan