Effects of IY-81149, a newly developed proton pump inhibitor, on gastric acid secretion in vitro and in vivo.

Kwon, D; Chae, J B; Park, C W; Kim, Y S; Lee, S M; Kim, E J; Huh, I H; Kim, D Y; Cho, K D

Kwon, D; Chae, J B; Park, C W; Kim, Y S; Lee, S M; Kim, E J; Huh, I H; Kim, D Y; Cho, K D.

Affiliation

Kwon D; Department of Pharmacology and Toxicology, Il Yang Central Research Institute, Kyunggi-Do, Korea.

Arzneimittelforschung ; 51(3): 204-13, 2001.

Article in En | MEDLINE | ID: mdl-11304936

Subject(s)

Anti-Ulcer Agents/pharmacology; Benzimidazoles/pharmacology; Enzyme Inhibitors/pharmacology; Gastric Acid/metabolism; Proton Pump Inhibitors; Sulfoxides/pharmacology; 2-Pyridinylmethylsulfinylbenzimidazoles; Aminopyrine/metabolism; Animals; Gastric Mucosa/drug effects; Gastric Mucosa/metabolism; Histamine/pharmacology; In Vitro Techniques; Male; Omeprazole/pharmacology; Pentagastrin/pharmacology; Rabbits; Rats; Rats, Sprague-Dawley; Stomach/drug effects

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Database: MEDLINE Main subject: Sulfoxides / Benzimidazoles / Enzyme Inhibitors / Proton Pump Inhibitors / Gastric Acid / Anti-Ulcer Agents Limits: Animals Language: En Journal: Arzneimittelforschung Year: 2001 Type: Article

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