Mutations in the novel membrane protein spinster interfere with programmed cell death and cause neural degeneration in Drosophila melanogaster.

Nakano, Y; Fujitani, K; Kurihara, J; Ragan, J; Usui-Aoki, K; Shimoda, L; Lukacsovich, T; Suzuki, K; Sezaki, M; Sano, Y; Ueda, R; Awano, W; Kaneda, M; Umeda, M; Yamamoto, D

Nakano, Y; Fujitani, K; Kurihara, J; Ragan, J; Usui-Aoki, K; Shimoda, L; Lukacsovich, T; Suzuki, K; Sezaki, M; Sano, Y; Ueda, R; Awano, W; Kaneda, M; Umeda, M; Yamamoto, D.

Affiliation

Nakano Y; ERATO Yamamoto Behavior Genes Project, Japan Science and Technology Corporation at Mitsubishi Kasei Institute of Life Sciences, Machida, Tokyo 194-8511, Japan.

Mol Cell Biol ; 21(11): 3775-88, 2001 Jun.

Article in En | MEDLINE | ID: mdl-11340170

Subject(s)

Apoptosis; Central Nervous System/pathology; Drosophila Proteins; Drosophila melanogaster/physiology; Insect Proteins/physiology; Membrane Proteins/physiology; Amino Acid Sequence; Animals; Animals, Genetically Modified; Base Sequence; Behavior, Animal; Central Nervous System/metabolism; DNA, Complementary; Drosophila melanogaster/genetics; Drosophila melanogaster/metabolism; Female; Humans; Insect Proteins/genetics; Insect Proteins/metabolism; Lipofuscin/metabolism; Membrane Proteins/genetics; Membrane Proteins/metabolism; Molecular Sequence Data; Mutagenesis; Nerve Degeneration; Neuroglia/metabolism; Ovarian Follicle/metabolism; Ovary/growth & development; Phenotype

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Full text: 1 Database: MEDLINE Main subject: Central Nervous System / Apoptosis / Insect Proteins / Drosophila Proteins / Drosophila melanogaster / Membrane Proteins Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Mol Cell Biol Year: 2001 Type: Article Affiliation country: Japan

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