Glutamate release promotes growth of malignant gliomas.

Takano, T; Lin, J H; Arcuino, G; Gao, Q; Yang, J; Nedergaard, M

Takano, T; Lin, J H; Arcuino, G; Gao, Q; Yang, J; Nedergaard, M.

Affiliation

Takano T; Department of Cell Biology, Anatomy and Pathology, New York Medical College, Valhalla, New York, USA.

Nat Med ; 7(9): 1010-5, 2001 Sep.

Article in En | MEDLINE | ID: mdl-11533703

Subject(s)

Amino Acid Transport System X-AG; Brain Neoplasms/metabolism; Brain Neoplasms/pathology; Glioma/metabolism; Glioma/pathology; Glutamic Acid/metabolism; Symporters; Animals; Brain Neoplasms/drug therapy; Carrier Proteins/metabolism; Cell Division/drug effects; Dizocilpine Maleate/pharmacology; Excitatory Amino Acid Antagonists/pharmacology; Glioma/drug therapy; Glutamate Plasma Membrane Transport Proteins; Luminescent Measurements; Male; Memantine/pharmacology; Neoplasm Transplantation; Neurons/metabolism; Neurons/pathology; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors; Tumor Cells, Cultured

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Database: MEDLINE Main subject: Brain Neoplasms / Glutamic Acid / Amino Acid Transport System X-AG / Symporters / Glioma Limits: Animals Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2001 Type: Article Affiliation country: United States

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