Manufacture of antithymocyte globulin (ATGAM) for clinical trials.

Wechter, W J; Nelson, J W; Perper, R J; Parcells, A J; Riebe, K W; Evans, J S; Satoh, P S; Ko, H

Wechter, W J; Nelson, J W; Perper, R J; Parcells, A J; Riebe, K W; Evans, J S; Satoh, P S; Ko, H.

Transplantation ; 28(4): 303-7, 1979 Oct.

Article in En | MEDLINE | ID: mdl-116400

ABSTRACT

ABSTRACT

Methods are described for preparing large amounts of horse anti-human thymocyte globulin (ATG, ATGAM; The Upjohn Company) for clinical use. These methods have been used since 1968 to provide material for clinical trials. Characteristics of 40 lots of ATG are summarized.

Subject(s)

Antilymphocyte Serum; T-Lymphocytes/immunology; Animals; Antilymphocyte Serum/analysis; Antilymphocyte Serum/standards; Antilymphocyte Serum/toxicity; Drug Compounding; Female; Haplorhini; Horses/immunology; Humans; Male

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Database: MEDLINE Main subject: T-Lymphocytes / Antilymphocyte Serum Limits: Animals / Female / Humans / Male Language: En Journal: Transplantation Year: 1979 Type: Article

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