RAG-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice.

Petiniot, Lisa K; Weaver, Zoë; Vacchio, Melanie; Shen, Rhuna; Wangsa, Danny; Barlow, Carrolee; Eckhaus, Michael; Steinberg, Seth M; Wynshaw-Boris, Anthony; Ried, Thomas; Hodes, Richard J

Petiniot, Lisa K; Weaver, Zoë; Vacchio, Melanie; Shen, Rhuna; Wangsa, Danny; Barlow, Carrolee; Eckhaus, Michael; Steinberg, Seth M; Wynshaw-Boris, Anthony; Ried, Thomas; Hodes, Richard J.

Affiliation

Petiniot LK; Experimental Immunology Branch, National Cancer Institute, Howard Hughes Medical Institute-NIH Research Scholars Program, National Institutes of Health, Bethesda, Maryland 20892, USA.

Mol Cell Biol ; 22(9): 3174-7, 2002 May.

Article in En | MEDLINE | ID: mdl-11940674

Subject(s)

DNA-Binding Proteins/genetics; Gene Rearrangement, B-Lymphocyte/genetics; Genes, RAG-1/genetics; Lymphoma/genetics; Protein Serine-Threonine Kinases/deficiency; Recombination, Genetic/genetics; Thymus Neoplasms/genetics; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; DNA Damage/genetics; DNA Repair/genetics; DNA-Binding Proteins/metabolism; Gene Deletion; Homeodomain Proteins/genetics; Homeodomain Proteins/metabolism; In Situ Hybridization, Fluorescence; Mice; Mice, Knockout; Protein Serine-Threonine Kinases/genetics; Survival Analysis; Time Factors; Translocation, Genetic/genetics; Tumor Suppressor Proteins

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Recombination, Genetic / Thymus Neoplasms / Gene Rearrangement, B-Lymphocyte / Genes, RAG-1 / Protein Serine-Threonine Kinases / DNA-Binding Proteins / Lymphoma Limits: Animals Language: En Journal: Mol Cell Biol Year: 2002 Type: Article Affiliation country: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google