Effects of aluminum and zinc on the oxidative stress caused by 6-hydroxydopamine autoxidation: relevance for the pathogenesis of Parkinson's disease.

Méndez-Alvarez, Estefanía; Soto-Otero, Ramón; Hermida-Ameijeiras, Alvaro; López-Real, Ana María; Labandeira-García, José Luis

Méndez-Alvarez, Estefanía; Soto-Otero, Ramón; Hermida-Ameijeiras, Alvaro; López-Real, Ana María; Labandeira-García, José Luis.

Affiliation

Méndez-Alvarez E; Grupo de Neuroquímica, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Santiago de Compostela, San Francisco 1, E-15782, Spain.

Biochim Biophys Acta ; 1586(2): 155-68, 2002 Mar 16.

Article in En | MEDLINE | ID: mdl-11959457

Subject(s)

Aluminum/pharmacology; Brain/drug effects; Oxidative Stress/drug effects; Zinc/pharmacology; Adrenergic Agents; Animals; Antioxidants/pharmacology; Ascorbic Acid/pharmacology; Brain/metabolism; Cations; Cysteine/pharmacology; Glutathione/pharmacology; Hydroxyl Radical/analysis; Hydroxyl Radical/metabolism; Male; Mitochondria/drug effects; Mitochondria/metabolism; Oxidopamine; Oxygen Consumption; Polarography; Rats; Rats, Sprague-Dawley; Spectrophotometry; Thiobarbituric Acid Reactive Substances/analysis

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Database: MEDLINE Main subject: Zinc / Brain / Oxidative Stress / Aluminum Type of study: Etiology_studies Limits: Animals Language: En Journal: Biochim Biophys Acta Year: 2002 Type: Article Affiliation country: Spain

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