Neutrophil elastase induces mucin production by ligand-dependent epidermal growth factor receptor activation.

Kohri, Kazuhiro; Ueki, Iris F; Nadel, Jay A

Kohri, Kazuhiro; Ueki, Iris F; Nadel, Jay A.

Affiliation

Kohri K; Cardiovascular Research Institute, University of California San Francisco, 94143-0130, USA.

Am J Physiol Lung Cell Mol Physiol ; 283(3): L531-40, 2002 Sep.

Article in En | MEDLINE | ID: mdl-12169572

Subject(s)

ErbB Receptors/physiology; Leukocyte Elastase/physiology; Antibodies/pharmacology; Cell Line; Enzyme Activation/physiology; ErbB Receptors/immunology; Free Radical Scavengers/pharmacology; Humans; Leukocyte Elastase/pharmacology; Ligands; Mitogen-Activated Protein Kinase Kinases/metabolism; Mucin 5AC; Mucins/antagonists & inhibitors; Mucins/biosynthesis; Peptide Hydrolases/metabolism; Protein Precursors/chemistry; Reactive Oxygen Species; Transforming Growth Factor alpha/chemistry; Transforming Growth Factor alpha/physiology

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Database: MEDLINE Main subject: Leukocyte Elastase / ErbB Receptors Limits: Humans Language: En Journal: Am J Physiol Lung Cell Mol Physiol Journal subject: BIOLOGIA MOLECULAR / FISIOLOGIA Year: 2002 Type: Article Affiliation country: United States

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