Autologous transplantation of genetically modified iris pigment epithelial cells: a promising concept for the treatment of age-related macular degeneration and other disorders of the eye.

Semkova, Irina; Kreppel, Florian; Welsandt, Gerhard; Luther, Thomas; Kozlowski, Jolanta; Janicki, Hanna; Kochanek, Stefan; Schraermeyer, Ulrich

Semkova, Irina; Kreppel, Florian; Welsandt, Gerhard; Luther, Thomas; Kozlowski, Jolanta; Janicki, Hanna; Kochanek, Stefan; Schraermeyer, Ulrich.

Affiliation

Semkova I; Center for Molecular Medicine Cologne (ZMMK), Center of Ophthalmology, Department of Retinal Surgery, Institute for Anatomy, University of Cologne, Kerpener Strasse 34, D-50931 Cologne, Germany.

Proc Natl Acad Sci U S A ; 99(20): 13090-5, 2002 Oct 01.

Article in En | MEDLINE | ID: mdl-12239351

Subject(s)

Aging; Cell Transplantation; Eye Diseases/therapy; Iris/cytology; Iris/metabolism; Macular Degeneration/therapy; Pigment Epithelium of Eye/cytology; Pigment Epithelium of Eye/metabolism; Adenoviridae/genetics; Animals; Cells, Cultured; Genetic Vectors; Green Fluorescent Proteins; Lasers; Luminescent Proteins/metabolism; Microscopy, Fluorescence; Rats; Rats, Long-Evans; Rats, Wistar; Recombinant Fusion Proteins/metabolism; Retina/metabolism; Retinitis Pigmentosa/therapy; Time Factors; Transplantation, Autologous

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Full text: 1 Database: MEDLINE Main subject: Pigment Epithelium of Eye / Aging / Iris / Cell Transplantation / Eye Diseases / Macular Degeneration Type of study: Prognostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2002 Type: Article Affiliation country: Germany

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