[Further clinical use of Dl-15-methyl-prostaglandin F2 alpha and testosterone propionate for termination of early pregnancy in outpatient department].

ABSTRACT

PIP 30 women with amenorrhea for up to 42 days were treated in the outpatient department, 29 for termination of early pregnancy and 1 for menstrual induction. The protocol of treatment was simplified. Testosterone propionate 100 mg was injected intramuscularly daily for 3 days, followed by a vaginal sponge containing 6 mg of d1-15-methyl-prostaglandin F2alpha (PGF2alpha) and then intramuscular injection of 2 mg of the same drug 6 hours later. Results of the 29 early pregnancy cases were 27 (93%) complete abortion and 2 (7%) incomplete abortions. A 3-day menstruation was induced in the nonpregnant case. With prophylactic use of fluphenazinum and diphenoxylate compound, the untoward reactions of vomiting and diarrhea were much reduced. The outpatient use of d1-15-methyl-PG and testosterone propionate is considered safe and pratical. (author's)^ieng