Co-crystallization of Staphylococcus aureus peptide deformylase (PDF) with potent inhibitors.

Harris, Melissa S; Bock, Jeffrey H; Choi, Gil; Cialdella, Joyce S; Curry, Kimberly A; Deibel, Martin R; Jacobsen, E Jon; Marshall, Vincent P; Murray, Robert W; Vosters, Anne F; Wolfe, Cindy L; Yem, Anthony W; Baldwin, Eric T

Harris, Melissa S; Bock, Jeffrey H; Choi, Gil; Cialdella, Joyce S; Curry, Kimberly A; Deibel, Martin R; Jacobsen, E Jon; Marshall, Vincent P; Murray, Robert W; Vosters, Anne F; Wolfe, Cindy L; Yem, Anthony W; Baldwin, Eric T.

Affiliation

Harris MS; Structural, Analytical and Medicinal Chemistry, Pharmacia Corporation, 301 Henrietta Street, Kalamazoo, MI 49007, USA. melissa.s.harris@pharmacia.com

Acta Crystallogr D Biol Crystallogr ; 58(Pt 12): 2153-6, 2002 Dec.

Article in En | MEDLINE | ID: mdl-12454484

Subject(s)

Amidohydrolases; Aminopeptidases/chemistry; Enzyme Inhibitors/chemistry; Staphylococcus aureus/enzymology; Aminopeptidases/antagonists & inhibitors; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors/pharmacology; Protein Conformation

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Database: MEDLINE Main subject: Staphylococcus aureus / Enzyme Inhibitors / Amidohydrolases / Aminopeptidases Language: En Journal: Acta Crystallogr D Biol Crystallogr Year: 2002 Type: Article Affiliation country: United States

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