VCAM-1-mediated Rac signaling controls endothelial cell-cell contacts and leukocyte transmigration.

van Wetering, Sandra; van den Berk, Nadia; van Buul, Jaap D; Mul, Frederik P J; Lommerse, Ingrid; Mous, Rogier; ten Klooster, Jean-Paul; Zwaginga, Jaap-Jan; Hordijk, Peter L

van Wetering, Sandra; van den Berk, Nadia; van Buul, Jaap D; Mul, Frederik P J; Lommerse, Ingrid; Mous, Rogier; ten Klooster, Jean-Paul; Zwaginga, Jaap-Jan; Hordijk, Peter L.

Affiliation

van Wetering S; Department of Experimental Immunohematology, Sanquin Research at CLB, 1066 CX Amsterdam, The Netherlands.

Am J Physiol Cell Physiol ; 285(2): C343-52, 2003 Aug.

Article in En | MEDLINE | ID: mdl-12700137

Subject(s)

Cell Adhesion/physiology; Cell Communication/physiology; Chemotaxis, Leukocyte/physiology; Endothelium, Vascular/metabolism; Leukocytes/metabolism; Vascular Cell Adhesion Molecule-1/metabolism; rac GTP-Binding Proteins/metabolism; ADP Ribose Transferases/pharmacology; Botulinum Toxins/pharmacology; Cell Adhesion/drug effects; Cell Communication/drug effects; Cell Line; Chemotaxis, Leukocyte/drug effects; Endothelium, Vascular/cytology; Endothelium, Vascular/drug effects; Enzyme Inhibitors/pharmacology; Humans; Interleukin-1/pharmacology; Leukocytes/cytology; Leukocytes/drug effects; Mitogen-Activated Protein Kinases/drug effects; Mitogen-Activated Protein Kinases/metabolism; Peptide Fragments/pharmacology; Reactive Oxygen Species/metabolism; Signal Transduction/drug effects; Signal Transduction/physiology; Vascular Cell Adhesion Molecule-1/drug effects; p38 Mitogen-Activated Protein Kinases; rac GTP-Binding Proteins/drug effects; rhoA GTP-Binding Protein/drug effects; rhoA GTP-Binding Protein/metabolism

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Database: MEDLINE Main subject: Endothelium, Vascular / Cell Adhesion / Cell Communication / Chemotaxis, Leukocyte / Vascular Cell Adhesion Molecule-1 / Rac GTP-Binding Proteins / Leukocytes Limits: Humans Language: En Journal: Am J Physiol Cell Physiol Journal subject: FISIOLOGIA Year: 2003 Type: Article Affiliation country: Netherlands

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