Melanopsin is required for non-image-forming photic responses in blind mice.

Panda, Satchidananda; Provencio, Ignacio; Tu, Daniel C; Pires, Susana S; Rollag, Mark D; Castrucci, Ana Maria; Pletcher, Mathew T; Sato, Trey K; Wiltshire, Tim; Andahazy, Mary; Kay, Steve A; Van Gelder, Russell N; Hogenesch, John B

Panda, Satchidananda; Provencio, Ignacio; Tu, Daniel C; Pires, Susana S; Rollag, Mark D; Castrucci, Ana Maria; Pletcher, Mathew T; Sato, Trey K; Wiltshire, Tim; Andahazy, Mary; Kay, Steve A; Van Gelder, Russell N; Hogenesch, John B.

Affiliation

Panda S; Genomics Institute of the Novartis Research Foundation, 10675 John J. Hopkins Drive, San Diego, CA 92121, USA.

Science ; 301(5632): 525-7, 2003 Jul 25.

Article in En | MEDLINE | ID: mdl-12829787

Subject(s)

Blindness/physiopathology; Light Signal Transduction; Light; Photoreceptor Cells, Vertebrate/physiology; Rod Opsins/physiology; Animals; Arylamine N-Acetyltransferase/genetics; Arylamine N-Acetyltransferase/metabolism; Blindness/genetics; Circadian Rhythm; Mice; Mice, Inbred C3H; Motor Activity; Reflex, Pupillary; Retinal Degeneration/genetics; Retinal Degeneration/physiopathology; Retinal Ganglion Cells/physiology; Rod Opsins/deficiency; Rod Opsins/genetics; Signal Transduction; Suprachiasmatic Nucleus/physiology

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Database: MEDLINE Main subject: Blindness / Rod Opsins / Photoreceptor Cells, Vertebrate / Light Signal Transduction / Light Limits: Animals Language: En Journal: Science Year: 2003 Type: Article Affiliation country: United States

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