Efficacious and orally bioavailable thrombin inhibitors based on a 2,5-thienylamidine at the P1 position: discovery of N-carboxymethyl-d-diphenylalanyl-l-prolyl[(5-amidino-2-thienyl)methyl]amide.
J Med Chem
; 46(17): 3612-22, 2003 Aug 14.
Article
in En
| MEDLINE
| ID: mdl-12904065
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Database:
MEDLINE
Main subject:
Protease Inhibitors
/
Sulfanilamides
/
Thrombin
/
Dipeptides
/
Amidines
Language:
En
Journal:
J Med Chem
Journal subject:
QUIMICA
Year:
2003
Type:
Article