Genotype-dependent time course of lymphocyte beta 2-adrenergic receptor down-regulation.

Bruck, Heike; Leineweber, Kirsten; Beilfuss, Anja; Weber, Melanie; Heusch, Gerd; Philipp, Thomas; Brodde, Otto-Erich

Bruck, Heike; Leineweber, Kirsten; Beilfuss, Anja; Weber, Melanie; Heusch, Gerd; Philipp, Thomas; Brodde, Otto-Erich.

Affiliation

Bruck H; Department of Pathophysiology and Nephrology, University of Essen Medical School, Germany.

Clin Pharmacol Ther ; 74(3): 255-63, 2003 Sep.

Article in En | MEDLINE | ID: mdl-12966369

Subject(s)

Down-Regulation/genetics; Genotype; Lymphocytes/metabolism; Receptors, Adrenergic, beta-2/biosynthesis; Receptors, Adrenergic, beta-2/genetics; Adrenergic beta-Agonists/pharmacokinetics; Adrenergic beta-Antagonists/pharmacokinetics; Adult; Binding Sites; Codon/genetics; Cyclic AMP/metabolism; Female; Heart Rate/drug effects; Humans; Iodocyanopindolol/pharmacokinetics; Kinetics; Male; Myocardial Contraction/drug effects; Polymorphism, Genetic/genetics; Terbutaline/pharmacokinetics

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Database: MEDLINE Main subject: Lymphocytes / Down-Regulation / Receptors, Adrenergic, beta-2 / Genotype Limits: Adult / Female / Humans / Male Language: En Journal: Clin Pharmacol Ther Year: 2003 Type: Article Affiliation country: Germany

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