3',5'-cyclic adenosine monophosphate-regulated enhancer binding (CREB) activity is required for normal growth and differentiated phenotype in the FRTL5 thyroid follicular cell line.

Woloshin, P I; Walton, K M; Rehfuss, R P; Goodman, R H; Cone, R D

Woloshin, P I; Walton, K M; Rehfuss, R P; Goodman, R H; Cone, R D.

Affiliation

Woloshin PI; Vollum Institute for Advanced Biomedical Research, Department of Cell Biology and Anatomy, Oregon Health Sciences University, Portland 92701-3098.

Mol Endocrinol ; 6(10): 1725-33, 1992 Oct.

Article in En | MEDLINE | ID: mdl-1333055

Subject(s)

Cell Differentiation/physiology; Cell Division/physiology; Cyclic AMP Response Element-Binding Protein/metabolism; Thyroid Gland/physiology; 3T3 Cells; Animals; Cell Line; Chloramphenicol O-Acetyltransferase/genetics; Chloramphenicol O-Acetyltransferase/metabolism; Cyclic AMP/metabolism; Cyclic AMP Response Element-Binding Protein/genetics; DNA/biosynthesis; Gene Expression; Kinetics; Mice; Mice, Inbred BALB C; Phenotype; RNA, Messenger/genetics; RNA, Messenger/metabolism; Rats; Recombinant Proteins/metabolism; Thymidine/metabolism; Thyroid Gland/cytology; Thyrotropin/pharmacology; Transfection

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Database: MEDLINE Main subject: Thyroid Gland / Cell Differentiation / Cell Division / Cyclic AMP Response Element-Binding Protein Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 1992 Type: Article

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