Neomycin is an agonist at a polyamine site on the N-methyl-D-aspartate receptor.

Pullan, L M; Stumpo, R J; Powel, R J; Paschetto, K A; Britt, M

Pullan, L M; Stumpo, R J; Powel, R J; Paschetto, K A; Britt, M.

Affiliation

Pullan LM; Department of Pharmacology, ICI Americas, Inc., Wilmington, DE 19897.

J Neurochem ; 59(6): 2087-93, 1992 Dec.

Article in En | MEDLINE | ID: mdl-1359015

Subject(s)

Neomycin/pharmacology; Polyamines/analysis; Receptors, N-Methyl-D-Aspartate/chemistry; Receptors, N-Methyl-D-Aspartate/physiology; Adrenergic alpha-Antagonists/pharmacology; Animals; Biguanides/pharmacology; Magnesium/pharmacology; Male; Phencyclidine/analogs & derivatives; Phencyclidine/metabolism; Piperazines/metabolism; Piperidines/pharmacology; Polyamines/pharmacology; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate/metabolism; Spermidine/pharmacology; Synaptic Membranes/ultrastructure; Tritium

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Database: MEDLINE Main subject: Polyamines / Neomycin / Receptors, N-Methyl-D-Aspartate Limits: Animals Language: En Journal: J Neurochem Year: 1992 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Polyamines / Neomycin / Receptors, N-Methyl-D-Aspartate Limits: Animals Language: En Journal: J Neurochem Year: 1992 Type: Article