Phosphoinositide 3-kinase regulates excitation-contraction coupling in neonatal cardiomyocytes.

McDowell, Susan A; McCall, Eileen; Matter, William F; Estridge, Thomas B; Vlahos, Chris J

McDowell, Susan A; McCall, Eileen; Matter, William F; Estridge, Thomas B; Vlahos, Chris J.

Affiliation

McDowell SA; Cardiovascular Research, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285-0520, USA.

Am J Physiol Heart Circ Physiol ; 286(2): H796-805, 2004 Feb.

Article in En | MEDLINE | ID: mdl-14563664

Subject(s)

Calcium/metabolism; Myocardial Contraction/physiology; Myocytes, Cardiac/physiology; Phosphatidylinositol 3-Kinases/physiology; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester/pharmacology; Animals; Animals, Newborn; Calcium Channels, L-Type/drug effects; Calcium Channels, L-Type/physiology; Calcium-Transporting ATPases/metabolism; Cells, Cultured; Chromones/pharmacology; Endoplasmic Reticulum/drug effects; Endoplasmic Reticulum/physiology; Enzyme Inhibitors/pharmacology; Heart Ventricles/drug effects; Kinetics; Morpholines/pharmacology; Myocytes, Cardiac/enzymology; Phosphoinositide-3 Kinase Inhibitors; Piperazines/pharmacology; Platelet-Derived Growth Factor/pharmacology; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel/physiology; Sarcoplasmic Reticulum/drug effects; Sarcoplasmic Reticulum/physiology; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Calcium Exchanger/metabolism; Ventricular Function

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Database: MEDLINE Main subject: Calcium / Phosphatidylinositol 3-Kinases / Myocytes, Cardiac / Myocardial Contraction Limits: Animals Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2004 Type: Article Affiliation country: United States

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