Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice.

Bruemmer, Dennis; Collins, Alan R; Noh, Grace; Wang, Wei; Territo, Mary; Arias-Magallona, Sarah; Fishbein, Michael C; Blaschke, Florian; Kintscher, Ulrich; Graf, Kristof; Law, Ronald E; Hsueh, Willa A

Bruemmer, Dennis; Collins, Alan R; Noh, Grace; Wang, Wei; Territo, Mary; Arias-Magallona, Sarah; Fishbein, Michael C; Blaschke, Florian; Kintscher, Ulrich; Graf, Kristof; Law, Ronald E; Hsueh, Willa A.

Affiliation

Bruemmer D; Division of Endocrinology, Diabetes and Hypertension, David Geffen School of Medicine, University of California, Los Angeles, Warren Hall, Suite 24-130, 900 Veteran Avenue, Los Angeles, California 90095, USA. whsueh@mednet.ucla.edu

J Clin Invest ; 112(9): 1318-31, 2003 Nov.

Article in En | MEDLINE | ID: mdl-14597759

Subject(s)

Angiotensin II/pharmacology; Aortic Aneurysm, Abdominal/etiology; Arteriosclerosis/etiology; Sialoglycoproteins/physiology; Animals; Aortic Aneurysm, Abdominal/therapy; Apolipoproteins E/physiology; Arteriosclerosis/therapy; Cell Movement; Cell Survival; Chemokine CCL2/physiology; Cytokines/biosynthesis; Gene Expression Regulation/drug effects; Leukocytes/physiology; Macrophages/physiology; Mice; Mice, Inbred C57BL; Osteopontin; RNA, Messenger/analysis; Receptors, CCR2; Receptors, Chemokine/physiology; Sialoglycoproteins/genetics

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Full text: 1 Database: MEDLINE Main subject: Arteriosclerosis / Sialoglycoproteins / Angiotensin II / Aortic Aneurysm, Abdominal Limits: Animals Language: En Journal: J Clin Invest Year: 2003 Type: Article Affiliation country: United States

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