Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

Rosenbauer, Frank; Wagner, Katharina; Kutok, Jeffery L; Iwasaki, Hiromi; Le Beau, Michelle M; Okuno, Yutaka; Akashi, Koichi; Fiering, Steven; Tenen, Daniel G

Rosenbauer, Frank; Wagner, Katharina; Kutok, Jeffery L; Iwasaki, Hiromi; Le Beau, Michelle M; Okuno, Yutaka; Akashi, Koichi; Fiering, Steven; Tenen, Daniel G.

Affiliation

Rosenbauer F; Harvard Institutes of Medicine, Room 954, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.

Nat Genet ; 36(6): 624-30, 2004 Jun.

Article in En | MEDLINE | ID: mdl-15146183

Subject(s)

Leukemia, Myeloid, Acute/etiology; Proto-Oncogene Proteins/deficiency; Trans-Activators/deficiency; Animals; Bone Marrow/pathology; Hematopoiesis; Humans; Karyotyping; Leukemia, Myeloid, Acute/genetics; Leukemia, Myeloid, Acute/metabolism; Leukemia, Myeloid, Acute/pathology; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Mice, Transgenic; Proto-Oncogene Proteins/genetics; Spleen/pathology; Trans-Activators/genetics

Search on Google

Add to My VHL

XML

PubMed Links

Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Trans-Activators / Proto-Oncogene Proteins Limits: Animals / Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2004 Type: Article Affiliation country: United States

Search on Google

Add to My VHL

XML

PubMed Links