A polymorphic CYP19 TTTA repeat influences aromatase activity and estrogen levels in elderly men: effects on bone metabolism.

Gennari, Luigi; Masi, Laura; Merlotti, Daniela; Picariello, Lucia; Falchetti, Alberto; Tanini, Annalisa; Mavilia, Carmelo; Del Monte, Francesca; Gonnelli, Stefano; Lucani, Barbara; Gennari, Carlo; Brandi, Maria Luisa

Gennari, Luigi; Masi, Laura; Merlotti, Daniela; Picariello, Lucia; Falchetti, Alberto; Tanini, Annalisa; Mavilia, Carmelo; Del Monte, Francesca; Gonnelli, Stefano; Lucani, Barbara; Gennari, Carlo; Brandi, Maria Luisa.

Affiliation

Gennari L; Department of Internal Medicine, University of Florence, 50139 Florence, Italy.

J Clin Endocrinol Metab ; 89(6): 2803-10, 2004 Jun.

Article in En | MEDLINE | ID: mdl-15181061

Subject(s)

Aromatase/genetics; Aromatase/metabolism; Bone and Bones/metabolism; Estrogens/blood; Osteoporosis/genetics; Polymorphism, Genetic; Aged; Aged, 80 and over; Bone Density/genetics; Bone and Bones/diagnostic imaging; Cohort Studies; Fibroblasts/physiology; Genetic Predisposition to Disease; Genotype; Humans; Longitudinal Studies; Male; Middle Aged; Osteoporosis/epidemiology; Repetitive Sequences, Nucleic Acid; Risk Factors; Skin/cytology; Ultrasonography

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Database: MEDLINE Main subject: Osteoporosis / Polymorphism, Genetic / Bone and Bones / Aromatase / Estrogens Type of study: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Aged / Aged80 / Humans / Male / Middle aged Language: En Journal: J Clin Endocrinol Metab Year: 2004 Type: Article Affiliation country: Italy

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