The two major human metapneumovirus genetic lineages are highly related antigenically, and the fusion (F) protein is a major contributor to this antigenic relatedness.

Skiadopoulos, Mario H; Biacchesi, Stéphane; Buchholz, Ursula J; Riggs, Jeffrey M; Surman, Sonja R; Amaro-Carambot, Emerito; McAuliffe, Josephine M; Elkins, William R; St  Claire, Marisa; Collins, Peter L; Murphy, Brian R

Skiadopoulos, Mario H; Biacchesi, Stéphane; Buchholz, Ursula J; Riggs, Jeffrey M; Surman, Sonja R; Amaro-Carambot, Emerito; McAuliffe, Josephine M; Elkins, William R; St Claire, Marisa; Collins, Peter L; Murphy, Brian R.

Affiliation

Skiadopoulos MH; Respiratory Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Disease, National Institutes of Health, Building 50, Room 6511, 50 South Dr., MSC 8007, Bethesda, MD 20892-8007, USA. mskiadopoulos@niaid.nih.gov

J Virol ; 78(13): 6927-37, 2004 Jul.

Article in En | MEDLINE | ID: mdl-15194769

Subject(s)

Antibodies, Viral/blood; Antigenic Variation; Metapneumovirus/genetics; Viral Fusion Proteins/immunology; Virus Replication; Animals; Antibodies, Viral/immunology; Base Sequence; Cell Line; Cricetinae; Cross Reactions; Disease Models, Animal; Humans; Metapneumovirus/immunology; Metapneumovirus/physiology; Molecular Sequence Data; Neutralization Tests; Pan troglodytes; Parainfluenza Virus 1, Human/genetics; Parainfluenza Virus 1, Human/immunology; Paramyxoviridae Infections/virology; Respiratory System/virology; Viral Fusion Proteins/chemistry; Viral Fusion Proteins/genetics

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Full text: 1 Database: MEDLINE Main subject: Virus Replication / Antigenic Variation / Viral Fusion Proteins / Metapneumovirus / Antibodies, Viral Limits: Animals / Humans Language: En Journal: J Virol Year: 2004 Type: Article Affiliation country: United States

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