Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die.

Ekert, Paul G; Read, Stuart H; Silke, John; Marsden, Vanessa S; Kaufmann, Hitto; Hawkins, Christine J; Gerl, Robert; Kumar, Sharad; Vaux, David L

Ekert, Paul G; Read, Stuart H; Silke, John; Marsden, Vanessa S; Kaufmann, Hitto; Hawkins, Christine J; Gerl, Robert; Kumar, Sharad; Vaux, David L.

Affiliation

Ekert PG; The Walter and Eliza Hall Institute for Medical Research, 1G Royal Parade, Parkville, Victoria 3050, Australia. ekert@wehi.edu.au

J Cell Biol ; 165(6): 835-42, 2004 Jun 21.

Article in En | MEDLINE | ID: mdl-15210730

Subject(s)

Apoptosis/physiology; Caspases/physiology; Cell Survival/physiology; Proteins/physiology; Animals; Apoptotic Protease-Activating Factor 1; Caspase 9; Caspases/deficiency; Caspases/genetics; Cell Line; Cell Survival/drug effects; Cytochromes c/analysis; Flow Cytometry; Gene Deletion; Interleukin-3/pharmacology; Mice; Mice, Knockout; Proteins/genetics; Tumor Cells, Cultured

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Full text: 1 Database: MEDLINE Main subject: Proteins / Cell Survival / Apoptosis / Caspases Limits: Animals Language: En Journal: J Cell Biol Year: 2004 Type: Article Affiliation country: Australia

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