Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase.

Liu, Wenshe; Peterson, Peter E; Carter, Richard J; Zhou, Xianzhi; Langston, James A; Fisher, Andrew J; Toney, Michael D

Liu, Wenshe; Peterson, Peter E; Carter, Richard J; Zhou, Xianzhi; Langston, James A; Fisher, Andrew J; Toney, Michael D.

Affiliation

Liu W; Department of Chemistry, University of California, Davis, California 95616, USA.

Biochemistry ; 43(34): 10896-905, 2004 Aug 31.

Article in En | MEDLINE | ID: mdl-15323550

Subject(s)

4-Aminobutyrate Transaminase/chemistry; 4-Aminobutyrate Transaminase/metabolism; Aminooxyacetic Acid/chemistry; Aminooxyacetic Acid/metabolism; Escherichia coli Proteins/chemistry; Escherichia coli Proteins/metabolism; 4-Aminobutyrate Transaminase/antagonists & inhibitors; Animals; Binding Sites; Carboxy-Lyases/antagonists & inhibitors; Carboxy-Lyases/chemistry; Carboxy-Lyases/metabolism; Crystallography, X-Ray; Enzyme Inhibitors/chemistry; Enzyme Inhibitors/metabolism; Escherichia coli Proteins/antagonists & inhibitors; Ligands; Models, Molecular; Protein Binding; Pyridoxal Phosphate/chemistry; Structural Homology, Protein; Substrate Specificity; Swine; Vigabatrin/chemistry; Vigabatrin/metabolism

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Database: MEDLINE Main subject: Escherichia coli Proteins / 4-Aminobutyrate Transaminase / Aminooxyacetic Acid Limits: Animals Language: En Journal: Biochemistry Year: 2004 Type: Article Affiliation country: United States

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