Airway hyper-reactivity mediated by B-1 cell immunoglobulin M antibody generating complement C5a at 1 day post-immunization in a murine hapten model of non-atopic asthma.

Kawikova, Ivana; Paliwal, Vipin; Szczepanik, Marian; Itakura, Atsuko; Fukui, Mieko; Campos, Regis A; Geba, Gregory P; Homer, Robert J; Iliopoulou, Bettina P; Pober, Jordan S; Tsuji, Ryohei F; Askenase, Philip W

Kawikova, Ivana; Paliwal, Vipin; Szczepanik, Marian; Itakura, Atsuko; Fukui, Mieko; Campos, Regis A; Geba, Gregory P; Homer, Robert J; Iliopoulou, Bettina P; Pober, Jordan S; Tsuji, Ryohei F; Askenase, Philip W.

Affiliation

Kawikova I; Section of Allergy and Clinical Immunology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA. ivana.kawikova@yale.edu

Immunology ; 113(2): 234-45, 2004 Oct.

Article in En | MEDLINE | ID: mdl-15379984

Subject(s)

Asthma/immunology; B-Lymphocytes/immunology; Bronchial Hyperreactivity/immunology; Complement C5a/immunology; Immunoglobulin M/immunology; Animals; Asthma/pathology; Asthma/physiopathology; Bronchial Hyperreactivity/pathology; Bronchoalveolar Lavage Fluid/cytology; Bronchoalveolar Lavage Fluid/immunology; Disease Models, Animal; Female; Haptens/immunology; Immunization/methods; Lung/pathology; Male; Methacholine Chloride/immunology; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Respiratory Function Tests; Respiratory System

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Full text: 1 Database: MEDLINE Main subject: Asthma / Immunoglobulin M / B-Lymphocytes / Complement C5a / Bronchial Hyperreactivity Limits: Animals Language: En Journal: Immunology Year: 2004 Type: Article Affiliation country: United States

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